Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands
dc.contributor.author | LeTellier, Paul R. | en_US |
dc.contributor.author | Smith, Jr. , William L. | en_US |
dc.contributor.author | Lands, William E. M. | en_US |
dc.date.accessioned | 2006-04-17T16:33:50Z | |
dc.date.available | 2006-04-17T16:33:50Z | |
dc.date.issued | 1973-12 | en_US |
dc.identifier.citation | LeTellier, Paul R., Smith, Jr., William L., Lands, William E. M. (1973/12)."Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands." Prostaglandins 4(6): 837-843. <http://hdl.handle.net/2027.42/33775> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T3H-47NVH88-8P/2/e899858e9c947cf7b590d210ae91346a | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/33775 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4205972&dopt=citation | en_US |
dc.description.abstract | A variety of agents that are known to complex copper can reversibly inhibit the oxygenation of unsaturated fatty acids by particulate preparations from sheep vesicular glands. The time-dependent activation of the oxygenase preparation by phenol, on the other hand, was not affected by the copper chelator, diethyldithiocarbamate. The results suggest that protein-bound copper could play a role in the interaction of the oxygenase enzyme with oxygen and the fatty acid substrates. Other findings indicate that phenanthroline type compounds may inhibit both the oxygenation reaction and phenol activation by binding to an hydrophobic site on the oxygenase. | en_US |
dc.format.extent | 271113 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Effect of metal-complexing agents on the oxygenase activity of sheep vesicular glands | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USA | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USA | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan 48104, USA | en_US |
dc.identifier.pmid | 4205972 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/33775/1/0000028.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0090-6980(73)90118-4 | en_US |
dc.identifier.source | Prostaglandins | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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