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Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus
dc.contributor.authorGunaga, K. P.en_US
dc.contributor.authorMenon, K. M. J.en_US
dc.date.accessioned2006-04-17T16:36:16Z
dc.date.available2006-04-17T16:36:16Z
dc.date.issued1973-09-05en_US
dc.identifier.citationGunaga, K. P., Menon, K. M. J. (1973/09/05)."Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus." Biochemical and Biophysical Research Communications 54(1): 440-448. <http://hdl.handle.net/2027.42/33815>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WBK-4DW335R-6D/2/cc745eadc2d3c972b1146c47e6c3c2baen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/33815
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4354950&dopt=citationen_US
dc.description.abstractEffect of different monoamines and estradiol were studied on cyclic AMP (cAMP) accumulation in hypothalami from 21 day old female rats. Incubation for 5 min with 10-4M epinephrine, norepinephrine or dopamine resulted in an increase in cAMP accumulation in the hypothalamus. Incubation of hypothalamic tissue with estradiol (4 x 10-7M to 2 x 10-5M) also resulted in an increase in cyclic AMP levels. The increase caused by estradiol was observed only after 50 min of incubation period. The estradiol induced increase in cyclic AMP accumulation was abolished by both [alpha] and [beta] blockers. These results suggest that the estradiol-induced increase in cyclic AMP may be mediated by a prior increase in catecholamines in the hypothalamic tissue.en_US
dc.format.extent410512 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleEffect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamusen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA; Reproductive Endocrinology Program Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA.en_US
dc.contributor.affiliationumReproductive Endocrinology Program Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA.en_US
dc.identifier.pmid4354950en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/33815/1/0000071.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0006-291X(73)90941-8en_US
dc.identifier.sourceBiochemical and Biophysical Research Communicationsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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