Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus
dc.contributor.author | Gunaga, K. P. | en_US |
dc.contributor.author | Menon, K. M. J. | en_US |
dc.date.accessioned | 2006-04-17T16:36:16Z | |
dc.date.available | 2006-04-17T16:36:16Z | |
dc.date.issued | 1973-09-05 | en_US |
dc.identifier.citation | Gunaga, K. P., Menon, K. M. J. (1973/09/05)."Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus." Biochemical and Biophysical Research Communications 54(1): 440-448. <http://hdl.handle.net/2027.42/33815> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6WBK-4DW335R-6D/2/cc745eadc2d3c972b1146c47e6c3c2ba | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/33815 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4354950&dopt=citation | en_US |
dc.description.abstract | Effect of different monoamines and estradiol were studied on cyclic AMP (cAMP) accumulation in hypothalami from 21 day old female rats. Incubation for 5 min with 10-4M epinephrine, norepinephrine or dopamine resulted in an increase in cAMP accumulation in the hypothalamus. Incubation of hypothalamic tissue with estradiol (4 x 10-7M to 2 x 10-5M) also resulted in an increase in cyclic AMP levels. The increase caused by estradiol was observed only after 50 min of incubation period. The estradiol induced increase in cyclic AMP accumulation was abolished by both [alpha] and [beta] blockers. These results suggest that the estradiol-induced increase in cyclic AMP may be mediated by a prior increase in catecholamines in the hypothalamic tissue. | en_US |
dc.format.extent | 410512 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Effect of catecholamines and ovarian hormones on cyclic AMP accumulation in rat hypothalamus | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA; Reproductive Endocrinology Program Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA. | en_US |
dc.contributor.affiliationum | Reproductive Endocrinology Program Department of Obstetrics and Gynecology, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA; Department of Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Michigan 48104, USA. | en_US |
dc.identifier.pmid | 4354950 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/33815/1/0000071.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0006-291X(73)90941-8 | en_US |
dc.identifier.source | Biochemical and Biophysical Research Communications | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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