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Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues

dc.contributor.authorMenon, K. M. J.en_US
dc.contributor.authorGiese, Sallyen_US
dc.contributor.authorJaffe, Robert B.en_US
dc.date.accessioned2006-04-17T16:40:54Z
dc.date.available2006-04-17T16:40:54Z
dc.date.issued1973-03-30en_US
dc.identifier.citationMenon, K. M. J., Giese, Sally, Jaffe, Robert B. (1973/03/30)."Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues." Biochimica et Biophysica Acta (BBA) - General Subjects 304(1): 203-209. <http://hdl.handle.net/2027.42/33916>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6T1W-47MCPBD-3Y/2/166ab606b919e277b6d31f0de0ebdb32en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/33916
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4349412&dopt=citationen_US
dc.description.abstractAdenylate cyclase activities have been assayed in the human fetal adrenal, heart ventricle, brain, liver, testis, kidney, skeletal muscle and lung during the first trimester of pregnancy. The requirements for adenylate cyclases are similar to those reported in all adult tissues. Of all tissues studied, heart ventricle had the highest level of enzymatic activity, and this tissue was most responsive to hormonal stimulation. Although adenylate cyclases from all of these tissues were stimulated by F- in vitro, hormonal stimulation was observed only in the liver, adrenal and heart ventricle. The presence of hormone-responsive adenylate cyclase in human fetal tissues suggests that cyclic AMP may be involved in gene expression.en_US
dc.format.extent357365 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleHormone- and fluoride-sensitive adenylate cyclases in human fetal tissuesen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMaterials Science and Engineeringen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelChemical Engineeringen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelEngineeringen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumReproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.contributor.affiliationumReproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.contributor.affiliationumReproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A.en_US
dc.identifier.pmid4349412en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/33916/1/0000182.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0304-4165(73)90129-3en_US
dc.identifier.sourceBiochimica et Biophysica Actaen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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