Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues
dc.contributor.author | Menon, K. M. J. | en_US |
dc.contributor.author | Giese, Sally | en_US |
dc.contributor.author | Jaffe, Robert B. | en_US |
dc.date.accessioned | 2006-04-17T16:40:54Z | |
dc.date.available | 2006-04-17T16:40:54Z | |
dc.date.issued | 1973-03-30 | en_US |
dc.identifier.citation | Menon, K. M. J., Giese, Sally, Jaffe, Robert B. (1973/03/30)."Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues." Biochimica et Biophysica Acta (BBA) - General Subjects 304(1): 203-209. <http://hdl.handle.net/2027.42/33916> | en_US |
dc.identifier.uri | http://www.sciencedirect.com/science/article/B6T1W-47MCPBD-3Y/2/166ab606b919e277b6d31f0de0ebdb32 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/33916 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4349412&dopt=citation | en_US |
dc.description.abstract | Adenylate cyclase activities have been assayed in the human fetal adrenal, heart ventricle, brain, liver, testis, kidney, skeletal muscle and lung during the first trimester of pregnancy. The requirements for adenylate cyclases are similar to those reported in all adult tissues. Of all tissues studied, heart ventricle had the highest level of enzymatic activity, and this tissue was most responsive to hormonal stimulation. Although adenylate cyclases from all of these tissues were stimulated by F- in vitro, hormonal stimulation was observed only in the liver, adrenal and heart ventricle. The presence of hormone-responsive adenylate cyclase in human fetal tissues suggests that cyclic AMP may be involved in gene expression. | en_US |
dc.format.extent | 357365 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Elsevier | en_US |
dc.title | Hormone- and fluoride-sensitive adenylate cyclases in human fetal tissues | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Reproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A. | en_US |
dc.contributor.affiliationum | Reproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A. | en_US |
dc.contributor.affiliationum | Reproductive Endocrinology Program, Departments of Obstetrics and Gynecology and Biological Chemistry, University of Michigan Medical Center, Ann Arbor, Mich. 48104, U.S.A. | en_US |
dc.identifier.pmid | 4349412 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/33916/1/0000182.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1016/0304-4165(73)90129-3 | en_US |
dc.identifier.source | Biochimica et Biophysica Acta | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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