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Laser microirradiation of the nucleolar organizer in cells of the rat kangaroo (Potorous tridactylis) : Reduction of nucleolar number and production of micronucleoli
dc.contributor.authorBerns, Michael W.en_US
dc.contributor.authorFloyd, Alton D.en_US
dc.contributor.authorAdkisson, Karen P.en_US
dc.contributor.authorCheng, Wanny K.en_US
dc.contributor.authorMoore, L.en_US
dc.contributor.authorHoover, G.en_US
dc.contributor.authorUstick, K.en_US
dc.contributor.authorBurgott, S.en_US
dc.contributor.authorOsial, T.en_US
dc.date.accessioned2006-04-17T16:44:27Z
dc.date.available2006-04-17T16:44:27Z
dc.date.issued1972-12en_US
dc.identifier.citationBerns, M. W., Floyd, A. D., Adkisson, K., Cheng, W. K., Moore, L., Hoover, G., Ustick, K., Burgott, S., Osial, T. (1972/12)."Laser microirradiation of the nucleolar organizer in cells of the rat kangaroo (Potorous tridactylis) : Reduction of nucleolar number and production of micronucleoli." Experimental Cell Research 75(2): 424-432. <http://hdl.handle.net/2027.42/33994>en_US
dc.identifier.urihttp://www.sciencedirect.com/science/article/B6WFC-4DW3402-J/2/3d79cb3bc4e6ce30bfa4e6c0db723738en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/33994
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4674695&dopt=citationen_US
dc.description.abstractCells of the established cell lines of the rat kangaroo (Protorous tridactylis), were laser microirradiated in order to study their nucleolar organizers. Microbeam irradiation of prophase and metaphase nucleolar organizer sites in both male (PTK1) and female (PTK2) cells resulted in a reduction in the number of normal nucleoli formed following mitosis. Irradiation of the one nucleolar organizer in the male cells, often resulted in the formation of numerous micronucleoli. Micronucleoli were also formed in small, extra nuclei, that were probably formed as a result of microirradiation of the centromere region of autosomes. Preliminary cytochemical analysis of the micronucleoli is presented and the possible mechanism of the formation is discussed.en_US
dc.format.extent10195425 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherElsevieren_US
dc.titleLaser microirradiation of the nucleolar organizer in cells of the rat kangaroo (Potorous tridactylis) : Reduction of nucleolar number and production of micronucleolien_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Zoology, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.contributor.affiliationumDepartment of Anatomy, University of Michigan, Ann Arbor, Mich. 48104, USAen_US
dc.identifier.pmid4674695en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/33994/1/0000266.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1016/0014-4827(72)90449-1en_US
dc.identifier.sourceExperimental Cell Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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