Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer
dc.contributor.author | Rubin, Mark A. | en_US |
dc.date.accessioned | 2006-04-19T13:36:33Z | |
dc.date.available | 2006-04-19T13:36:33Z | |
dc.date.issued | 2001-09 | en_US |
dc.identifier.citation | Rubin, Mark A. (2001)."Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer." The Journal of Pathology 195(1): 80-86. <http://hdl.handle.net/2027.42/34485> | en_US |
dc.identifier.issn | 0022-3417 | en_US |
dc.identifier.issn | 1096-9896 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/34485 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=11568894&dopt=citation | en_US |
dc.description.abstract | One difficulty in studying epithelial tumors has been the inability to isolate pure samples for DNA and RNA analysis. Prostate cancer, with its infiltrative nature, is particularly challenging. The Combination of several new technologies should help overcome these hurdles. Laser capture microdissection uses a laser beam to achieve transfer of pure cell populations for isolation of DNA, RNA, and protein. High-throughput analysis of these samples can be achieved by using cDNA expression microarrays. High-density tissue microarrays should allow for validation of differentially expressed genes. This review will concentrate on the application of laser capture microdissection, cDNA microarrays, and tissue microarrays in the area of prostate cancer research. Copyright © 2001 John Wiley & Sons, Ltd. | en_US |
dc.format.extent | 289370 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Ltd. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cancer Research, Oncology and Pathology | en_US |
dc.title | Use of laser capture microdissection, cDNA microarrays, and tissue microarrays in advancing our understanding of prostate cancer | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pathology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Pathology, Urology, and the Comprehensive Cancer and Geriatrics Center of the University of Michigan, Ann Arbor, MI 48109, USA ; Departments of Pathology and Urology, University of Michigan, 1500 E. Medical Center Drive, Room 2G332/Box 0054, Ann Arbor, MI 48109-0054, USA. http://rubinlab.cancer.med.umich.edu | en_US |
dc.identifier.pmid | 11568894 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/34485/1/892_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/path.892 | en_US |
dc.identifier.source | The Journal of Pathology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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