Semen quality and fertility of men employed in a South African lead acid battery plant
dc.contributor.author | Robins, Thomas G. | en_US |
dc.contributor.author | Bornman, M. S. | en_US |
dc.contributor.author | Ehrlich, Rodney I. | en_US |
dc.contributor.author | Cantrell, Anthony C. | en_US |
dc.contributor.author | Pienaar, Elma | en_US |
dc.contributor.author | Vallabh, Jawaherlal | en_US |
dc.contributor.author | Miller, Shirley | en_US |
dc.date.accessioned | 2006-04-19T13:52:11Z | |
dc.date.available | 2006-04-19T13:52:11Z | |
dc.date.issued | 1997-10 | en_US |
dc.identifier.citation | Robins, Thomas G.; Bornman, M.S.; Ehrlich, Rodney I.; Cantrell, Anthony C.; Pienaar, Elma; Vallabh, Jawaherlal; Miller, Shirley (1997)."Semen quality and fertility of men employed in a South African lead acid battery plant." American Journal of Industrial Medicine 32(4): 369-376. <http://hdl.handle.net/2027.42/34817> | en_US |
dc.identifier.issn | 0271-3586 | en_US |
dc.identifier.issn | 1097-0274 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/34817 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9258391&dopt=citation | en_US |
dc.description.abstract | Previous studies of the associations of measures of occupational lead exposure with measures of semen quality and infertility among male workers have produced conflicting results. The current study was undertaken to examine these associations among a population of workers with a broad range of measures of current and historical lead exposure. Ninety-seven lead-exposed workers from a South African lead acid battery facility provided semen samples that were analyzed for sperm density, sperm count, sperm motility, sperm morphology, and presence of antisperm antibodies. Questionnaire data were collected for reported histories of sub- or infertility. Current blood leads ranged from 28 to 93 μg/dl. Semen lead ranged from 1 to 87 μg/dl. Reasonably consistent and significant associations were found between an increased percentage of sperm with abnormal morphology and higher measures of current blood lead, cumulative blood lead, and duration of exposure. An increased percent of immotile sperm was associated only with zinc protoporphyrin (ZPP) among the lead exposure measures. There were no associations of sperm density or sperm count with any of the lead exposure measures. A weak association of increased percent of sperm with antisperm antibodies with increased semen lead was present. There were no consistent associations of measures of lead exposure with measures of fertility or procreativity. This study, while supporting the association of lead exposure with increased risk of abnormal sperm morphology seen in some previous studies, does not lend support to previously reported associations of sperm density or count or infertility with measures of lead exposure. However, the relatively high range of current blood leads, high prevalence of abnormalities in semen quality, and the lack of a control population, suggest that these negative findings should be interpreted with caution. Am. J. Ind. Med. 32:369–376, 1997. © 1997 Wiley-Liss, Inc. | en_US |
dc.format.extent | 53387 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Occupational Health and Environmental Toxicology | en_US |
dc.title | Semen quality and fertility of men employed in a South African lead acid battery plant | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Environmental and Industrial Health, University of Michigan School of Public Health, Ann Arbor, Michigan ; Department of Environmental and Industrial Health, University of Michigan School of Public Health, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationother | Department of Urology, University of PretoriaPretoria, South Africa | en_US |
dc.contributor.affiliationother | Department of Community Health, University of Cape Town, Cape Town, South Africa | en_US |
dc.contributor.affiliationother | National Centre for Occupational Health, Johannesburg, South Africa ; Department of Community Health, University of Witwatersrand, Witwatersrand, South Africa | en_US |
dc.contributor.affiliationother | Department of Urology, University of PretoriaPretoria, South Africa | en_US |
dc.contributor.affiliationother | National Centre for Occupational Health, Johannesburg, South Africa | en_US |
dc.contributor.affiliationother | Chemical Workers Industrial Union, Johannesburg, South Africa | en_US |
dc.identifier.pmid | 9258391 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/34817/1/8_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/(SICI)1097-0274(199710)32:4<369::AID-AJIM8>3.0.CO;2-P | en_US |
dc.identifier.source | American Journal of Industrial Medicine | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.