Analysis of a zebrafish semaphorin reveals potential functions in vivo
dc.contributor.author | Halloran, Mary C. | en_US |
dc.contributor.author | Severance, Shawn M. | en_US |
dc.contributor.author | Yee, Charles S. | en_US |
dc.contributor.author | Gemza, Debra L. | en_US |
dc.contributor.author | Raper, Jonathan A. | en_US |
dc.contributor.author | Kuwada, John Y. | en_US |
dc.date.accessioned | 2006-04-19T14:13:46Z | |
dc.date.available | 2006-04-19T14:13:46Z | |
dc.date.issued | 1999-01 | en_US |
dc.identifier.citation | Halloran, Mary C.; Severance, Shawn M.; Yee, Charles S.; Gemza, Debra L.; Raper, Jonathan A.; Kuwada, John Y. (1999)."Analysis of a zebrafish semaphorin reveals potential functions in vivo." Developmental Dynamics 214(1): 13-25. <http://hdl.handle.net/2027.42/35164> | en_US |
dc.identifier.issn | 1058-8388 | en_US |
dc.identifier.issn | 1097-0177 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/35164 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9915572&dopt=citation | en_US |
dc.description.abstract | The semaphorin/collapsin gene family is a large and diverse family encoding both secreted and transmembrane proteins, some of which are thought to act as repulsive axon guidance molecules. However, the function of most semaphorins is still unknown. We have cloned and characterized several semaphorins in the zebrafish in order to assess their in vivo function. Zebrafish semaZ2 is expressed in a dynamic and restricted pattern during the period of axon outgrowth that indicates potential roles in the guidance of several axon pathways. Analysis of mutant zebrafish with reduced semaZ2 expression reveals axon pathfinding errors that implicate SemaZ2 in normal guidance. Dev Dyn 1999;214:13–25. © 1999 Wiley-Liss, Inc. | en_US |
dc.format.extent | 1231418 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Analysis of a zebrafish semaphorin reveals potential functions in vivo | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Pediatrics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Biology, University of Michigan, Ann Arbor, Michigan ; Department of Biology, University of Michigan, Ann Arbor, MI 48109–1048. | en_US |
dc.contributor.affiliationother | Department of Neuroscience, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania | en_US |
dc.identifier.pmid | 9915572 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/35164/1/2_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/(SICI)1097-0177(199901)214:1<13::AID-DVDY2>3.0.CO;2-3 | en_US |
dc.identifier.source | Developmental Dynamics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.