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Influence of natural and synthetic estrogens on the course of autoimmune disease in the nzb/nzw mouse
dc.contributor.authorWalker, Sara Ellenen_US
dc.contributor.authorBole, Giles G.en_US
dc.date.accessioned2006-04-28T16:21:17Z
dc.date.available2006-04-28T16:21:17Z
dc.date.issued1973-03en_US
dc.identifier.citationWalker, Sara Ellen; Bole, Giles G (1973)."Influence of natural and synthetic estrogens on the course of autoimmune disease in the nzb/nzw mouse." Arthritis & Rheumatism 16(2): 231-239. <http://hdl.handle.net/2027.42/37723>en_US
dc.identifier.issn0004-3591en_US
dc.identifier.issn1529-0131en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/37723
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4123763&dopt=citationen_US
dc.description.abstractAntinuclear antibodies were found in 64% of serum samples obtained from male NZB/NZW mice after 6 weeks of treatment with mestranol. Both female and male mice responded to this synthetic female hormone with marked elevations of serum Α 2 - and Β-globulins; Γ-globulins were not increased. There was no evidence that mestranol accelerated the development of autoimmune renal disease in these animals. Treatment of hybrid New Zealand mice with mestranol, 17-Β-estradiol and oophorectomy exerts divergent effects on serum proteins and the development of serologic abnormalities.en_US
dc.format.extent764140 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherJohn Wiley & Sons, Inc.en_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherRheumatologyen_US
dc.titleInfluence of natural and synthetic estrogens on the course of autoimmune disease in the nzb/nzw mouseen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelGeriatricsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumRackham Arthritis Research Unit, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Mich. ; R4633 Kresge Building, University of Michigan Medical Center, Ann Arbor, Mich. 48104en_US
dc.contributor.affiliationumRackham Arthritis Research Unit, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Mich.en_US
dc.identifier.pmid4123763en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/37723/1/1780160215_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/art.1780160215en_US
dc.identifier.sourceArthritis & Rheumatismen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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