Identification of brain lesions in neuropsychiatric systemic lupus erythematosus by magnetic resonance scanning
dc.contributor.author | McCune, William Joseph | en_US |
dc.contributor.author | Macguire, Anne | en_US |
dc.contributor.author | Aisen, Alex M. | en_US |
dc.contributor.author | Gebarski, Stephen S. | en_US |
dc.date.accessioned | 2006-04-28T16:24:10Z | |
dc.date.available | 2006-04-28T16:24:10Z | |
dc.date.issued | 1988-02 | en_US |
dc.identifier.citation | Mccune, W. Joseph; Macguire, Anne; Aisen, Alex; Gebarski, Stephen (1988)."Identification of brain lesions in neuropsychiatric systemic lupus erythematosus by magnetic resonance scanning." Arthritis & Rheumatism 31(2): 159-166. <http://hdl.handle.net/2027.42/37779> | en_US |
dc.identifier.issn | 0004-3591 | en_US |
dc.identifier.issn | 1529-0131 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/37779 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3348821&dopt=citation | en_US |
dc.description.abstract | Cranial magnetic resonance imaging in 28 systemic lupus erythematosus patients who had experienced 30 acute neuropsychiatric events showed focal brain lesions in 16 of 30 events (53%) and low brain volume (atrophy) in 20 of 30 events (67%). Definite focal lesions were significantly more frequent in patients with clinically localized neurologic deficits (8 of 8, 100%), or seizures (5 of 6, 83%) than in patients without such localizing signs (3 of 16, 19%). Many of these lesions were occult on intravenous contrast-enhanced x-ray computed tomography. In 2 patients, lesions in gray matter resolved within 2 or 3 weeks, in association with clinical improvement. Magnetic resonance imaging is an important technique for detecting the extent of brain injury in cerebral lupus. | en_US |
dc.format.extent | 815681 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc. | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Rheumatology | en_US |
dc.title | Identification of brain lesions in neuropsychiatric systemic lupus erythematosus by magnetic resonance scanning | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Geriatrics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Medicine and Radiology, University of Michigan Hospitals, Ann Arbor. ; University of Michigan Hospitals, 3918 Taubman Center, Ann Arbor, MI 48109–0358 | en_US |
dc.contributor.affiliationum | Departments of Medicine and Radiology, University of Michigan Hospitals, Ann Arbor. | en_US |
dc.contributor.affiliationum | Departments of Medicine and Radiology, University of Michigan Hospitals, Ann Arbor. | en_US |
dc.contributor.affiliationum | Departments of Medicine and Radiology, University of Michigan Hospitals, Ann Arbor. | en_US |
dc.identifier.pmid | 3348821 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/37779/1/1780310202_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/art.1780310202 | en_US |
dc.identifier.source | Arthritis & Rheumatism | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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