The calculated circular dichroism of polyproline ii in the polarizability approximation
dc.contributor.author | Ronish, E. W. | en_US |
dc.contributor.author | Krimm, Samuel | en_US |
dc.date.accessioned | 2006-04-28T16:26:58Z | |
dc.date.available | 2006-04-28T16:26:58Z | |
dc.date.issued | 1974-08 | en_US |
dc.identifier.citation | Ronish, E. W.; Krimm, S. (1974)."The calculated circular dichroism of polyproline ii in the polarizability approximation." Biopolymers 13(8): 1635-1651. <http://hdl.handle.net/2027.42/37836> | en_US |
dc.identifier.issn | 0006-3525 | en_US |
dc.identifier.issn | 1097-0282 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/37836 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4418254&dopt=citation | en_US |
dc.description.abstract | The circular dichroism (CD) spectrum of polyproline II (PPII) has heretofore been moderately well calculated from exciton theory only at the expense of assuming unreasonable chain conformations and accepting a conservative spectrum in the 180–250-nm region (which is not observed). We have incorporated far uv transitions in the polarizability approximation and, together with the Π 2 Π* transition, have calculated the resulting correction to the exciton model. This has been accompanied by a modified assignment of the ΠΠ* transition in PPII, and a simultaneous calculation of the absorption and CD spectra of the Α-helix, Β structure, PPI, and PPII. We obtain good agreement with the observed CD spectrum of PPII in the 180–250-nm region for acceptable chain conformations. In addition, we predict a negative CD into the far uv, in agreement with recent experimental observations. Our calculations also reproduce features of the far uv CD spectrum of the Α-helix, and are in agreement with the CD spectra of the Β chain and PPI. The calculated CD of the unordered polypeptide chain is not significantly influenced by far uv contributions, indicating that our previous calculation is valid for such a system. These results demonstrate the importance of incorporating far uv transitions in order to achieve an adequate theoretical explanation of the CD spectra of polypeptides. | en_US |
dc.format.extent | 809517 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Chemistry | en_US |
dc.subject.other | Polymer and Materials Science | en_US |
dc.title | The calculated circular dichroism of polyproline ii in the polarizability approximation | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Materials Science and Engineering | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Harrison M. Randall Laboratory of Physics, University of Michigan, Ann Arbor, Michigan 48104 | en_US |
dc.contributor.affiliationum | Harrison M. Randall Laboratory of Physics, University of Michigan, Ann Arbor, Michigan 48104 | en_US |
dc.identifier.pmid | 4418254 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/37836/1/360130810_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/bip.1974.360130810 | en_US |
dc.identifier.source | Biopolymers | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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