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Computer aided analysis for biosensing and screening

dc.contributor.authorLi, Xiang-Mingen_US
dc.contributor.authorLiang, Bernard S.en_US
dc.contributor.authorWang, Henry Y.en_US
dc.date.accessioned2006-04-28T16:29:52Z
dc.date.available2006-04-28T16:29:52Z
dc.date.issued1988-02-20en_US
dc.identifier.citationLi, Xiang-Ming; Liang, Bernard S.; Wang, Henry Y. (1988)."Computer aided analysis for biosensing and screening." Biotechnology and Bioengineering 31(3): 250-256. <http://hdl.handle.net/2027.42/37895>en_US
dc.identifier.issn0006-3592en_US
dc.identifier.issn1097-0290en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/37895
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=18584600&dopt=citationen_US
dc.description.abstractBiosensors with animal and microbial cells immobilized close to the tip of a membrane electrode have been developed for chemical and drug testing. Our experimental results show that biosensors can be used for drug screening and to provide useful information about various cell-chemical interactions. A computer aided analysis (CAA) software package is being developed here using the biosensor for various screening purposes. This software package enables us to use a computer to analyze the biosensor dynamic responses. Computer simulation and parameter estimation techniques are used to select the best model and to describe the biochemical and pharmacologic effects of various chemicals and drugs on different cell lines.en_US
dc.format.extent563349 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherChemistryen_US
dc.subject.otherBiochemistry and Biotechnologyen_US
dc.titleComputer aided analysis for biosensing and screeningen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbsecondlevelMathematicsen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelStatistics and Numeric Dataen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.contributor.affiliationumDepartment of Chemical Engineering, University of Michigan, Ann Arbor, Michigan 48109en_US
dc.identifier.pmid18584600en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/37895/1/260310311_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/bit.260310311en_US
dc.identifier.sourceBiotechnology and Bioengineeringen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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