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dc.contributor.authorSearls, Robert L.en_US
dc.contributor.authorJanners, Martha Y.en_US
dc.date.accessioned2006-04-28T16:38:41Z
dc.date.available2006-04-28T16:38:41Z
dc.date.issued1969-03en_US
dc.identifier.citationSearls, Robert L.; Janners, Martha Y. (1969)."The stabilization of cartilage properties in the cartilage-forming mesenchyme of the embryonic chick limb This research was supported in part by N.S.F. research grant G.B. 4846. This is the fifth paper in a series on the differentiation of cartilage in the limb bud of the embryonic chick. Some of the research reported in this paper was performed at the Biology Department; University of Virginia, Charlottesville, Virginia, and has appeared in preliminary from (Am. Zool., 7 ('67)). Requests for information concerning this paper should be sent to Robert L. Searls, Department of Biology, Temple University, Philadelphia, Pa. ." Journal of Experimental Zoology 170(3): 365-375. <http://hdl.handle.net/2027.42/38068>en_US
dc.identifier.issn0022-104Xen_US
dc.identifier.issn1097-010Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/38068
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5795332&dopt=citationen_US
dc.description.abstractExperiments have been done to determine the time in the development of the embryonic chick limb when the cells in the cartilage-forming area become “stabilized.” The particular criterion for stability used in this work was the ability of the cells to resist the influences in the limb which cause some limb mesenchyme cell to form cartilage and other limb mesenchyme cells to form soft tissue. Blocks of cartilage-forming mesenchyme were transplanted from the cartilage-forming area of a second limb to the prospective soft tissue area of a second limb. The host limb was permitted to develop for 48 hours, and then examined to determine if the implanted cells had formed cartilage outside of the normal cartilage pattern of the host limb. The embryos used as a source of the implanted blocks varied in stage from stage 22 to stage 27, the hosts also varied in stage from stage 22 to stage 27. It was found that a block of cartilage-forming mesenchyme generally would conform with the host limb pattern if the donor was stage 24 or younger and the host was stage 24 or younger. A block of cartilage-forming mesenchyme generally did not conform with the host limb pattern if the donor was stage 25 or older whatever the stage of the host. We conclude that the cartilage-forming cells become stabilized by this criterion between stage 24 and stage 25.en_US
dc.format.extent1597384 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherCell & Developmental Biologyen_US
dc.titleThe stabilization of cartilage properties in the cartilage-forming mesenchyme of the embryonic chick limben_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Biology, Temple University, Philadelphia, Pa. 19122, and University of Michigan, Dearborn Campus, Dearborn, Mich. 48128en_US
dc.contributor.affiliationumDepartment of Biology, Temple University, Philadelphia, Pa. 19122, and University of Michigan, Dearborn Campus, Dearborn, Mich. 48128en_US
dc.identifier.pmid5795332en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/38068/1/1401700313_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/jez.1401700313en_US
dc.identifier.sourceJournal of Experimental Zoologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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