Influence of sex-linked genes on embryonic sensitivity to cortisone in three strains of mice Supported by NIH grant 5 T01 GM00071. The contents of this paper form a part of the author's dissertation submitted as a partial requirement for the Ph.D. degree at the University of Michigan under the direction of Professor Morris Foster.
dc.contributor.author | Francis, B. M. | en_US |
dc.date.accessioned | 2006-04-28T16:41:32Z | |
dc.date.available | 2006-04-28T16:41:32Z | |
dc.date.issued | 1973-04 | en_US |
dc.identifier.citation | Francis, B. M. (1973)."Influence of sex-linked genes on embryonic sensitivity to cortisone in three strains of mice Supported by NIH grant 5 T01 GM00071. The contents of this paper form a part of the author's dissertation submitted as a partial requirement for the Ph.D. degree at the University of Michigan under the direction of Professor Morris Foster. ." Teratology 7(2): 119-125. <http://hdl.handle.net/2027.42/38124> | en_US |
dc.identifier.issn | 0040-3709 | en_US |
dc.identifier.issn | 1096-9926 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38124 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4725543&dopt=citation | en_US |
dc.description.abstract | It was postulated that sex-linked genes affecting embryonic sensitivity to cortisone-induced cleft palate and cortisone-induced resorption might differ between inbred mouse strains showing pronounced reciprocal effects. The three strains tested were the A/J (A), C57BL/6J (B), and C3H/HeJ (C), whose sensitivities to cortisone-induced cleft palate had been shown to be: A > C > B. The sensitivity of reciprocal A × B and B × C hybrid embryos was matroclinous; of reciprocal A × C embryos, patroclinous. Backcrosses of reciprocal F 1 hybrid males to inbred females were used to test the hypothesis of sex-linkage with respect to the incidence of cortisone-induced cleft palate, cortisone-induced resorption, and the overall level of cortisone-induced fetal damage. The results were consistent with the hypothesis that sex-linked genes affecting embryonic sensitivity to cortisone-induced cleft palate, but not to cortisone-induced resorption, differ in the three strains. | en_US |
dc.format.extent | 534507 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cell & Developmental Biology | en_US |
dc.title | Influence of sex-linked genes on embryonic sensitivity to cortisone in three strains of mice Supported by NIH grant 5 T01 GM00071. The contents of this paper form a part of the author's dissertation submitted as a partial requirement for the Ph.D. degree at the University of Michigan under the direction of Professor Morris Foster. | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Area Program in Genetics, University of Michigan, Ann Arbor, Michigan 48104 | en_US |
dc.identifier.pmid | 4725543 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38124/1/1420070202_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/tera.1420070202 | en_US |
dc.identifier.source | Teratology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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