Hormonal regulation of membrane phenotype
dc.contributor.author | Carlson, Sarah A. | en_US |
dc.contributor.author | Gelehrter, Thomas D. | en_US |
dc.date.accessioned | 2006-04-28T16:45:38Z | |
dc.date.available | 2006-04-28T16:45:38Z | |
dc.date.issued | 1977 | en_US |
dc.identifier.citation | Carlson, Sarah A.; Gelehrter, Thomas D. (1977)."Hormonal regulation of membrane phenotype." Journal of Supramolecular Structure 6(3): 325-331. <http://hdl.handle.net/2027.42/38204> | en_US |
dc.identifier.issn | 0091-7419 | en_US |
dc.identifier.issn | 1547-9366 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38204 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=201807&dopt=citation | en_US |
dc.description.abstract | Incubation of rat hepatoma cells (HTC) in tissue culture with glucocorticoids alters several membrane properties characteristic of transformed cells, without affecting the growth rate of these cells. Variant cell lines resistant to dexamethasone inhibition of plasminogen activator production have been isolated using an agar-fibrin overlay technique to detect plasminogen activator production by individual colonies of HTC cells. The resistance to dexamethasone is not secondary to abnormal or absent glucocorticoid receptors, but due to a lesion in a later step in hormone action specific for plasminogen activator. These variants should prove useful for the study of the mechanism of steroid action as well as for the analysis of the role of proteases in the hormonal regulation of membrane function. | en_US |
dc.format.extent | 386829 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Alan R. Liss, Inc. | en_US |
dc.publisher | Wiley Periodiocals, Inc. | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Molecular Cell Biology | en_US |
dc.title | Hormonal regulation of membrane phenotype | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Departments of Human Genetics and Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 | en_US |
dc.identifier.pmid | 201807 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38204/1/400060305_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/jss.400060305 | en_US |
dc.identifier.source | Journal of Supramolecular Structure | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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