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Phenotypic heterogeneity in cystic fibrosis

dc.contributor.authorSing, Charles F.en_US
dc.contributor.authorRisser, David R.en_US
dc.contributor.authorHowatt, William F.en_US
dc.contributor.authorErickson, Robert P.en_US
dc.date.accessioned2006-04-28T16:47:25Z
dc.date.available2006-04-28T16:47:25Z
dc.date.issued1982-10en_US
dc.identifier.citationSing, Charles F.; Risser, David R.; Howatt, William F.; Erickson, Robert P. (1982)."Phenotypic heterogeneity in cystic fibrosis." American Journal of Medical Genetics 13(2): 179-195. <http://hdl.handle.net/2027.42/38234>en_US
dc.identifier.issn0148-7299en_US
dc.identifier.issn1096-8628en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/38234
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7137230&dopt=citationen_US
dc.description.abstractWe have confirmed heterogenity in CF using a different combination of primary clinical variables than those used in previous studies. Subgroupings of individuals with similar levels of sweat chloride were independent of the clustering based on level of pancreatic enzyme supplementation and degree of pulmonary involvement. Data from families with multiple CF children are consistent with the hypothesis that the genetic etiology of CF involves two or more genes that modify the expression of the primary gene defect.en_US
dc.format.extent936972 bytes
dc.format.extent3118 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherWiley Subscription Services, Inc., A Wiley Companyen_US
dc.subject.otherLife and Medical Sciencesen_US
dc.subject.otherGeneticsen_US
dc.titlePhenotypic heterogeneity in cystic fibrosisen_US
dc.typeArticleen_US
dc.rights.robotsIndexNoFollowen_US
dc.subject.hlbsecondlevelGeneticsen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartments of Human Genetics, University of Michigan, Ann Arbor ; Department of Human Genetics, University of Michigan, 1137 E. Catherine Street, Ann Arbor, MI 48109en_US
dc.contributor.affiliationumDepartments of Human Genetics, University of Michigan, Ann Arboren_US
dc.contributor.affiliationumDepartment of Pediatrics, Mott Children's Hospital, University of Michigan, Ann Arboren_US
dc.contributor.affiliationumDepartments of Human Genetics, University of Michigan, Ann Arbor ; Departments of Pediatrics, University of Michigan, Ann Arboren_US
dc.identifier.pmid7137230en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/38234/1/1320130209_ftp.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1002/ajmg.1320130209en_US
dc.identifier.sourceAmerican Journal of Medical Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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