Phenotypic heterogeneity in cystic fibrosis
dc.contributor.author | Sing, Charles F. | en_US |
dc.contributor.author | Risser, David R. | en_US |
dc.contributor.author | Howatt, William F. | en_US |
dc.contributor.author | Erickson, Robert P. | en_US |
dc.date.accessioned | 2006-04-28T16:47:25Z | |
dc.date.available | 2006-04-28T16:47:25Z | |
dc.date.issued | 1982-10 | en_US |
dc.identifier.citation | Sing, Charles F.; Risser, David R.; Howatt, William F.; Erickson, Robert P. (1982)."Phenotypic heterogeneity in cystic fibrosis." American Journal of Medical Genetics 13(2): 179-195. <http://hdl.handle.net/2027.42/38234> | en_US |
dc.identifier.issn | 0148-7299 | en_US |
dc.identifier.issn | 1096-8628 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38234 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7137230&dopt=citation | en_US |
dc.description.abstract | We have confirmed heterogenity in CF using a different combination of primary clinical variables than those used in previous studies. Subgroupings of individuals with similar levels of sweat chloride were independent of the clustering based on level of pancreatic enzyme supplementation and degree of pulmonary involvement. Data from families with multiple CF children are consistent with the hypothesis that the genetic etiology of CF involves two or more genes that modify the expression of the primary gene defect. | en_US |
dc.format.extent | 936972 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Genetics | en_US |
dc.title | Phenotypic heterogeneity in cystic fibrosis | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Genetics | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Human Genetics, University of Michigan, Ann Arbor ; Department of Human Genetics, University of Michigan, 1137 E. Catherine Street, Ann Arbor, MI 48109 | en_US |
dc.contributor.affiliationum | Departments of Human Genetics, University of Michigan, Ann Arbor | en_US |
dc.contributor.affiliationum | Department of Pediatrics, Mott Children's Hospital, University of Michigan, Ann Arbor | en_US |
dc.contributor.affiliationum | Departments of Human Genetics, University of Michigan, Ann Arbor ; Departments of Pediatrics, University of Michigan, Ann Arbor | en_US |
dc.identifier.pmid | 7137230 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38234/1/1320130209_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/ajmg.1320130209 | en_US |
dc.identifier.source | American Journal of Medical Genetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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