Imaging of nodal metastases in the head and neck
dc.contributor.author | Anzai, Yoshimi | en_US |
dc.contributor.author | Brunberg, James A. | en_US |
dc.contributor.author | Lufkin, Robert B. | en_US |
dc.date.accessioned | 2006-04-28T17:05:11Z | |
dc.date.available | 2006-04-28T17:05:11Z | |
dc.date.issued | 1997-09 | en_US |
dc.identifier.citation | Anzai, Yoshimi; Brunberg, James A.; Lufkin, Robert B. (1997)."Imaging of nodal metastases in the head and neck." Journal of Magnetic Resonance Imaging 7(5): 774-783. <http://hdl.handle.net/2027.42/38576> | en_US |
dc.identifier.issn | 1053-1807 | en_US |
dc.identifier.issn | 1522-2586 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38576 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9307901&dopt=citation | en_US |
dc.description.abstract | Therapeutic outcome of head and neck cancer is influenced strongly by the presence of nodal metastases. Sensitivity and specificity of the physical examination for the diagnosis of nodal metastasis is unsatisfactory, resulting in both false negatives and false positives of 25 to 40%. Preoperative detection of nodal metastases therefore becomes one of the important goals of imaging studies of patients with head and neck cancer. Despite several advanced techniques and the wide clinical use of MR, MR has surprisingly added little to the diagnostic accuracy of contrast-enhanced CT. Although CT and MR allow detection of abnormally enlarged nodes or necrotic nodes, neither borderline-sized nodes without necrosis nor extracapsular spread are reliably differentiated from reactive or normal nodes in patients with head and neck cancer. Lack of definitive diagnostic methods of metastatic lymph nodes is a serious shortcoming in the preoperative workup for patients with head and neck cancer. To avoid missing small metastatic nodes, a large number of patients clinically staged as NO have undergone elective neck dissection to exclude metastases. With development of more tissue-specific imaging techniques, patients can be better characterized according to the status of nodal disease so that an appropriate therapeutic protocol can be designed for an individual case. | en_US |
dc.format.extent | 1024 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/octet-stream | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Imaging | en_US |
dc.title | Imaging of nodal metastases in the head and neck | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Medicine (General) | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Radiology, the University of Michigan Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0030 ; Department of Radiology, the University of Michigan Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0030 | en_US |
dc.contributor.affiliationum | Department of Radiology, the University of Michigan Hospital, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0030 | en_US |
dc.contributor.affiliationother | Department of Radiological Sciences, University of California, Los Angeles, CA | en_US |
dc.identifier.pmid | 9307901 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38576/1/sgml.22796 | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/jmri.1880070503 | en_US |
dc.identifier.source | Journal of Magnetic Resonance Imaging | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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