Synthesis of optically active polynucleotide analogs with polytrimethylenimine backbones and thymine moieties
dc.contributor.author | Overberger, Charles Gilbert | en_US |
dc.contributor.author | Chang, Ji Young | en_US |
dc.contributor.author | Gunn, V. E. | en_US |
dc.date.accessioned | 2006-04-28T18:19:00Z | |
dc.date.available | 2006-04-28T18:19:00Z | |
dc.date.issued | 1989-01-15 | en_US |
dc.identifier.citation | Overberger, C. G.; Chang, Ji Young; Gunn, V. E. (1989)."Synthesis of optically active polynucleotide analogs with polytrimethylenimine backbones and thymine moieties." Journal of Polymer Science Part A: Polymer Chemistry 27(1): 99-106. <http://hdl.handle.net/2027.42/38837> | en_US |
dc.identifier.issn | 0887-624X | en_US |
dc.identifier.issn | 1099-0518 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/38837 | |
dc.description.abstract | Polynucleotide analogs with polytrimethylenimine backbones and optically active 2-(thymin-1-yl)propionic acids as pendants were prepared. Linear polytrimethylenimines were obtained by ring-opening polymerization of 2-phenyl-5,6-dyhydro-4H-1,3-oxazine and subsequent hydrolysis of the resulting polymers. 2-(Thymin-1-yl)propionic acids were reacted with N -hydroxy succinimide to form active esters. Optical purities of active esters were determined by NMR with chiral chemical shift reagents. The polynucloetide analogs and related monomer and dimer model compounds were prepared by grafting reactions using active esters. | en_US |
dc.format.extent | 410044 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | John Wiley & Sons, Inc. | en_US |
dc.subject.other | Chemistry | en_US |
dc.subject.other | Polymer and Materials Science | en_US |
dc.title | Synthesis of optically active polynucleotide analogs with polytrimethylenimine backbones and thymine moieties | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Chemical Engineering | en_US |
dc.subject.hlbtoplevel | Engineering | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Chemistry and the Macromolecular Research Center, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Chemistry and the Macromolecular Research Center, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.contributor.affiliationum | Department of Chemistry and the Macromolecular Research Center, The University of Michigan, Ann Arbor, Michigan 48109 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/38837/1/080270109_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/pola.1989.080270109 | en_US |
dc.identifier.source | Journal of Polymer Science Part A: Polymer Chemistry | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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