Interobserver reliability of computed tomography-derived primary tumor volume measurement in patients with supraglottic carcinoma
dc.contributor.author | Mukherji, Suresh K. | en_US |
dc.contributor.author | Toledano, Alicia Y. | en_US |
dc.contributor.author | Beldon, Clifford | en_US |
dc.contributor.author | Schmalfuss, Ilona M. | en_US |
dc.contributor.author | Cooper, Jay S. | en_US |
dc.contributor.author | Sicks, JoRean D. | en_US |
dc.contributor.author | Amdur, Robert | en_US |
dc.contributor.author | Sailer, Scott | en_US |
dc.contributor.author | Loevner, Laurie A. | en_US |
dc.contributor.author | Kousouboris, Phil | en_US |
dc.contributor.author | Ang, Kian | en_US |
dc.date.accessioned | 2006-06-21T14:16:49Z | |
dc.date.available | 2006-06-21T14:16:49Z | |
dc.date.issued | 2005-06-15 | en_US |
dc.identifier.citation | Mukherji, Suresh K.; Toledano, Alicia Y.; Beldon, Clifford; Schmalfuss, Ilona M.; Cooper, Jay S.; Sicks, JoRean D.; Amdur, Robert; Sailer, Scott; Loevner, Laurie A.; Kousouboris, Phil; Ang, Kian (2005)."Interobserver reliability of computed tomography-derived primary tumor volume measurement in patients with supraglottic carcinoma." Cancer 103(12): 2616-2622. <http://hdl.handle.net/2027.42/39198> | en_US |
dc.identifier.issn | 0008-543X | en_US |
dc.identifier.issn | 1097-0142 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/39198 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=15887218&dopt=citation | en_US |
dc.description.abstract | BACKGROUND Prior studies have determined that macroscopic (“gross”) tumor volume (GTV), as calculated from pretreatment computer tomography (CT), was capable of predicting local control in squamous cell carcinoma arising in different subsites in the head and neck in patients who were treated with nonsurgical organ-preservation therapy. The majority of these studies were single-institution, retrospective investigations. Consequently, there has been concern that GTV measurements may not be reproducible by different readers at different institutions. The objective of the current study was to measure the interobserver reliability for GTV measurements for squamous cell carcinoma of the supraglottic larynx (SGSCCA) performed by different readers at different institutions. METHODS Eight experienced readers (4 neuroradiologists and 4 radiation oncologists) from different institutions independently measured the pretreatment GTV of 20 patients with SGSCCA. The CT scans were obtained from patients entered into the definitive radiation therapy arm of Radiation Therapy Oncology Group protocol 91-11, who had supraglottic carcinoma and underwent pretreatment CT scans of the neck. Statistical analysis focused on interobserver reliability as measured by the intraclass correlation coefficient. RESULTS The intraclass correlation coefficient was 0.81 (95% lower confidence bound, 0.71). This value was interpreted as “excellent.” CONCLUSIONS GTV measurements were reliable and reproducible when performed by neuroradiologists and radiation oncologists who were experienced in the interpretation of CT scans of the extracranial head and neck in patients with SGSCCA. The result implied that the correlation between GTV and local control should be reproducible across institutions. Cancer 2005. © 2005 American Cancer Society. | en_US |
dc.format.extent | 145944 bytes | |
dc.format.extent | 3118 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Wiley Subscription Services, Inc., A Wiley Company | en_US |
dc.subject.other | Life and Medical Sciences | en_US |
dc.subject.other | Cancer Research, Oncology and Pathology | en_US |
dc.title | Interobserver reliability of computed tomography-derived primary tumor volume measurement in patients with supraglottic carcinoma | en_US |
dc.type | Article | en_US |
dc.rights.robots | IndexNoFollow | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Radiology, University of Michigan Health System, Ann Arbor, Michigan ; Department of Otolaryngology/Head Neck Surgery, University of Michigan Health System, Ann Arbor, Michigan ; Fax: (734) 764-2412 ; Department of Radiology, B2A209, University of Michigan Health Systems, 1500 East Medical Center Drive, Ann Arbor, MI 48109-0030 | en_US |
dc.contributor.affiliationother | Center for Statistical Sciences, Brown University, Providence, Rhode Island | en_US |
dc.contributor.affiliationother | Department of Radiology, State University of New York, Albany Medical School, Albany, New York | en_US |
dc.contributor.affiliationother | Department of Radiology, University of Florida College of Medicine, Gainesville, Florida | en_US |
dc.contributor.affiliationother | Department of Radiation Oncology, New York University School of Medicine, New York, New York | en_US |
dc.contributor.affiliationother | Center for Statistical Sciences, Brown University, Providence, Rhode Island | en_US |
dc.contributor.affiliationother | Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida | en_US |
dc.contributor.affiliationother | Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, North Carolina | en_US |
dc.contributor.affiliationother | Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania | en_US |
dc.contributor.affiliationother | Department of Radiology, Bryn Mawr Hospital, Bryn Mawr, Pennsylvania | en_US |
dc.contributor.affiliationother | Department of Radiation Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas | en_US |
dc.identifier.pmid | 15887218 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/39198/1/21072_ftp.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1002/cncr.21072 | en_US |
dc.identifier.source | Cancer | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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