Activation of T lymphocytes for the adoptive immunotherapy of cancer
dc.contributor.author | Shu, Suyu | en_US |
dc.contributor.author | Chang, Alfred E. | en_US |
dc.contributor.author | Sussman, Jeffrey J. | en_US |
dc.contributor.author | Sondak, Vernon K. | en_US |
dc.date.accessioned | 2006-09-08T19:12:57Z | |
dc.date.available | 2006-09-08T19:12:57Z | |
dc.date.issued | 1994-07 | en_US |
dc.identifier.citation | Sussman, Jeffrey J.; Shu, Suyu; Sondak, Vernon K.; Chang, Alfred E.; (1994). "Activation of T lymphocytes for the adoptive immunotherapy of cancer." Annals of Surgical Oncology 1(4): 296-306. <http://hdl.handle.net/2027.42/41399> | en_US |
dc.identifier.issn | 1068-9265 | en_US |
dc.identifier.issn | 1534-4681 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41399 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7850528&dopt=citation | en_US |
dc.description.abstract | Background: Adoptive immunotherapy of malignancy involves the passive transfer of antitumor-reactive cells into a host in order to mediate tumor regression. Based on animal models, the transfer of immune lymphoid cells can eradicate widely disseminated tumors and establish long-term systemic immunity. Critical for successful adoptive immunotherapy is the ability to isolate large numbers of immune cells. For clinical therapy, it will require the development of in vitro methods to promote the sensitization and propagation of tumor-reactive cells. However, this is formidable task since human cancers are postulated to be poorly immunogenic because of their spontaneous origins. | en_US |
dc.format.extent | 1414768 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; The Society of Surgical Oncology, Inc. | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Surgery | en_US |
dc.subject.other | Antitumor-reactive Cells | en_US |
dc.subject.other | Lymphoid Cells | en_US |
dc.subject.other | Tumor Regression | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Adoptive Immunotherapy | en_US |
dc.subject.other | Surgical Oncology | en_US |
dc.title | Activation of T lymphocytes for the adoptive immunotherapy of cancer | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | From the Division of Surgical Oncology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | From the Division of Surgical Oncology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | From the Division of Surgical Oncology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | From the Division of Surgical Oncology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 7850528 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41399/1/10434_2006_Article_BF02303568.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF02303568 | en_US |
dc.identifier.source | Annals of Surgical Oncology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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