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Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model

dc.contributor.authorWeiner, Norman D.en_US
dc.contributor.authorTurner, Jason H.en_US
dc.contributor.authorPaasch, Brian D.en_US
dc.contributor.authorShort, Sarah M.en_US
dc.contributor.authorDaugherty, Ann L.en_US
dc.date.accessioned2006-09-08T19:16:29Z
dc.date.available2006-09-08T19:16:29Z
dc.date.issued1996-07en_US
dc.identifier.citationShort, Sarah M.; Paasch, Brian D.; Turner, Jason H.; Weiner, Norman; Daugherty, Ann L.; (1996). "Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model." Pharmaceutical Research 13(7): 1020-1027. <http://hdl.handle.net/2027.42/41453>en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.issn0724-8741en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41453
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8842039&dopt=citationen_US
dc.description.abstractPurpose . Topical delivery has been suggested to reduce systemic side effects while targeting cytokines for the treatment of certain skin conditions. Liposomes have been proposed as an enhancing agent for such a delivery. We have tested the potential of liposomes to augment the uptake of biologically active recombinant human interferon-gamma (rhIFN-γ) into human skin lacking adnexa in an in vivo model.en_US
dc.format.extent14200640 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherHuman Skin Graften_US
dc.subject.otherLiposomesen_US
dc.subject.otherPharmacyen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherNude Mouseen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherRhIFN-γen_US
dc.subject.otherTopical Deliveryen_US
dc.subject.otherBiomedicineen_US
dc.titlePercutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Modelen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationotherBioAnalytical Methods Development, Genentech Inc., South San Francisco, California, 94080-4990en_US
dc.contributor.affiliationotherPharmaceutical Research and Development, Genentech Inc., 460 Pt. San Bruno Blvd., South San Francisco, California, 94080-4990; Department Pharmacology, University of North Carolina, Chapel Hill, North Carolina, 27599en_US
dc.contributor.affiliationotherBioAnalytical Methods Development, Genentech Inc., South San Francisco, California, 94080-4990en_US
dc.contributor.affiliationotherPharmaceutical Research and Development, Genentech Inc., 460 Pt. San Bruno Blvd., South San Francisco, California, 94080-4990en_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid8842039en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41453/1/11095_2004_Article_306664.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1016050422634en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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