Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model
dc.contributor.author | Weiner, Norman D. | en_US |
dc.contributor.author | Turner, Jason H. | en_US |
dc.contributor.author | Paasch, Brian D. | en_US |
dc.contributor.author | Short, Sarah M. | en_US |
dc.contributor.author | Daugherty, Ann L. | en_US |
dc.date.accessioned | 2006-09-08T19:16:29Z | |
dc.date.available | 2006-09-08T19:16:29Z | |
dc.date.issued | 1996-07 | en_US |
dc.identifier.citation | Short, Sarah M.; Paasch, Brian D.; Turner, Jason H.; Weiner, Norman; Daugherty, Ann L.; (1996). "Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model." Pharmaceutical Research 13(7): 1020-1027. <http://hdl.handle.net/2027.42/41453> | en_US |
dc.identifier.issn | 1573-904X | en_US |
dc.identifier.issn | 0724-8741 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41453 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8842039&dopt=citation | en_US |
dc.description.abstract | Purpose . Topical delivery has been suggested to reduce systemic side effects while targeting cytokines for the treatment of certain skin conditions. Liposomes have been proposed as an enhancing agent for such a delivery. We have tested the potential of liposomes to augment the uptake of biologically active recombinant human interferon-gamma (rhIFN-γ) into human skin lacking adnexa in an in vivo model. | en_US |
dc.format.extent | 14200640 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Human Skin Graft | en_US |
dc.subject.other | Liposomes | en_US |
dc.subject.other | Pharmacy | en_US |
dc.subject.other | Medical Law | en_US |
dc.subject.other | Nude Mouse | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | RhIFN-γ | en_US |
dc.subject.other | Topical Delivery | en_US |
dc.subject.other | Biomedicine | en_US |
dc.title | Percutaneous Absorption of Biologically-Active Interferon-gamma in a Human Skin Graft-Nude Mouse Model | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | College of Pharmacy, University of Michigan, Ann Arbor, Michigan, 48109-1065 | en_US |
dc.contributor.affiliationother | BioAnalytical Methods Development, Genentech Inc., South San Francisco, California, 94080-4990 | en_US |
dc.contributor.affiliationother | Pharmaceutical Research and Development, Genentech Inc., 460 Pt. San Bruno Blvd., South San Francisco, California, 94080-4990; Department Pharmacology, University of North Carolina, Chapel Hill, North Carolina, 27599 | en_US |
dc.contributor.affiliationother | BioAnalytical Methods Development, Genentech Inc., South San Francisco, California, 94080-4990 | en_US |
dc.contributor.affiliationother | Pharmaceutical Research and Development, Genentech Inc., 460 Pt. San Bruno Blvd., South San Francisco, California, 94080-4990 | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 8842039 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41453/1/11095_2004_Article_306664.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1016050422634 | en_US |
dc.identifier.source | Pharmaceutical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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