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Reduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorption
dc.contributor.authorCook, Chyungen_US
dc.contributor.authorKirchhoff, Carolen_US
dc.contributor.authorPao, Li-Hengen_US
dc.contributor.authorKarim, Azizen_US
dc.contributor.authorTruelove, Jamesen_US
dc.contributor.authorZhou, Simon Yujien_US
dc.contributor.authorKararli, Tugrulen_US
dc.contributor.authorFleisher, Daviden_US
dc.date.accessioned2006-09-08T19:17:12Z
dc.date.available2006-09-08T19:17:12Z
dc.date.issued1998-02en_US
dc.identifier.citationPao, Li-Heng; Zhou, Simon Yuji; Cook, Chyung; Kararli, Tugrul; Kirchhoff, Carol; Truelove, James; Karim, Aziz; Fleisher, David; (1998). "Reduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorption." Pharmaceutical Research 15(2): 221-227. <http://hdl.handle.net/2027.42/41464>en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.issn0724-8741en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41464
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=9523307&dopt=citationen_US
dc.description.abstractPurpose . The aim of this research was to determine the mechanism by which a co-administered meal decreases the oral absorption of bidisomide and does not influence the oral absorption of the chemically-related antiarrhythmic agent, disopyramide.en_US
dc.format.extent631254 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherCanine Modelen_US
dc.subject.otherBidisomideen_US
dc.subject.otherViscosityen_US
dc.subject.otherDisopyramideen_US
dc.subject.otherIntestinal Clearanceen_US
dc.subject.otherSite-specific Absorptionen_US
dc.subject.otherPharmacyen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherDrug Absorptionen_US
dc.subject.otherFood Effectsen_US
dc.subject.otherRegional-dependent Absorptionen_US
dc.titleReduced Systemic Availability of an Antiarrhythmic Drug, Bidisomide, with Meal Co-administration: Relationship with Region-Dependent Intestinal Absorptionen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065; School of Pharmacy, National Defense Medical Center, P.O. Box 90048-508, Taipei, Taiwan, Republic of Chinaen_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065en_US
dc.contributor.affiliationotherG.D. Searle & Co., 4901 Searle Parkway, Skokie, Illinois, 60077en_US
dc.contributor.affiliationotherG.D. Searle & Co., 4901 Searle Parkway, Skokie, Illinois, 60077en_US
dc.contributor.affiliationotherG.D. Searle & Co., 4901 Searle Parkway, Skokie, Illinois, 60077en_US
dc.contributor.affiliationotherG.D. Searle & Co., 4901 Searle Parkway, Skokie, Illinois, 60077en_US
dc.contributor.affiliationotherG.D. Searle & Co., 4901 Searle Parkway, Skokie, Illinois, 60077en_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid9523307en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41464/1/11095_2004_Article_303802.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1011958400362en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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