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Regulation of Paracellular Absorption of Cimetidine and 5-Aminosalicylate in Rat Intestine
dc.contributor.authorZhou, Simon Yujien_US
dc.contributor.authorLiu, Guangyuen_US
dc.contributor.authorPiyapolrungroj, Nusaraen_US
dc.contributor.authorZimmermann, Ellen M.en_US
dc.contributor.authorLi, Chengen_US
dc.contributor.authorFleisher, Daviden_US
dc.contributor.authorPao, Li-Hengen_US
dc.date.accessioned2006-09-08T19:17:44Z
dc.date.available2006-09-08T19:17:44Z
dc.date.issued1999-11en_US
dc.identifier.citationZhou, Simon Yuji; Piyapolrungroj, Nusara; Pao, Li-heng; Li, Cheng; Liu, Guangyu; Zimmermann, Ellen; Fleisher, David; (1999). "Regulation of Paracellular Absorption of Cimetidine and 5-Aminosalicylate in Rat Intestine." Pharmaceutical Research 16(11): 1781-1785. <http://hdl.handle.net/2027.42/41472>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41472
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=10571287&dopt=citationen_US
dc.description.abstractPurpose . Isolating the relative contributions of parallel transcellular and paracellular transport to the intestinal absorption of small hydrophilic molecules has proven experimentally challenging. In this report, lumenal appearance of drug metabolite is utilized as a tool to assess the contribution of paracellular transport to the absorption of cimetidine and 5-aminosalicylate (5ASA) in rat small intestine.en_US
dc.format.extent977839 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherCimetidineen_US
dc.subject.other5-aminosalicylateen_US
dc.subject.otherParacellular Transporten_US
dc.subject.otherIntestinal Absorptionen_US
dc.subject.otherIntestinal Metabolismen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherPharmacyen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherMedical Lawen_US
dc.titleRegulation of Paracellular Absorption of Cimetidine and 5-Aminosalicylate in Rat Intestineen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48105-1065en_US
dc.contributor.affiliationumDepartment of Internal Medicine, The University of Michigan, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationumCollege of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48105-1065en_US
dc.contributor.affiliationotherDepartment of Pharmacy, Silpakorn University, Nakorn-pathom, 73000, Thailanden_US
dc.contributor.affiliationotherDrug Metabolism and Pharmacokinetics, Schering-Plough Research Institute, Kenilworth, New Jersey, 07033-1300en_US
dc.contributor.affiliationotherCandidate Synthesis Enhancement and Evaluation, Pfizer Central Research, Eastern Point Road, Groton, Connecticut, 06340en_US
dc.contributor.affiliationotherSchool of Pharmacy, National Defense Medical Center, Taipei, Taiwan, ROCen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid10571287en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41472/1/11095_2004_Article_303737.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1018974519984en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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