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Radiolabeled Cholesteryl lopanoate/ Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbits

dc.contributor.authorCounsell, Raymond E.en_US
dc.contributor.authorScott, T.en_US
dc.contributor.authorXiao, W.en_US
dc.contributor.authorWang, L.en_US
dc.contributor.authorLiu, H.en_US
dc.date.accessioned2006-09-08T19:18:00Z
dc.date.available2006-09-08T19:18:00Z
dc.date.issued1999-03en_US
dc.identifier.citationXiao, W.; Wang, L.; Scott, T.; Counsell, R. E.; Liu, H.; (1999). "Radiolabeled Cholesteryl lopanoate/ Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbits." Pharmaceutical Research 16(3): 420-426. <http://hdl.handle.net/2027.42/41476>en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.issn0724-8741en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41476
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=10213374&dopt=citationen_US
dc.description.abstractPurpose . Atherosclerosis is the underlying factor leading to such cardiovascular diseases (CVD) as stroke, aneurysm, and myocardial infarction. The early detection of atherosclerotic plaques is considered to be crucial for successful prevention and/or therapeutic and dietary intervention of CVD. Current diagnostic practice, on the other hand, can only detect the problem at an advanced stage. The purpose of this study was to examine the potential of using a radiolabeled cholesterol ester analog/acetylated low density lipoprotein (AcLDL) conjugate as a diagnostic agent for the early and non-invasive detection of atherosclerosis and for the monitoring of the effects of drug therapy.en_US
dc.format.extent2915137 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherAutoradiographyen_US
dc.subject.otherCholesteryl Iopanoateen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherMedical Lawen_US
dc.subject.otherAtherosclerosisen_US
dc.subject.otherVisualizationen_US
dc.subject.otherDiagnostic Agenten_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherAcLDLen_US
dc.titleRadiolabeled Cholesteryl lopanoate/ Acetylated Low Density Lipoprotein as a Potential Probe for Visualization of Early Atherosclerotic Lesions in Rabbitsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan Medical School, Ann Arbor, Michigan, 48109en_US
dc.contributor.affiliationotherSchool of Pharmacy, Memorial University of Newfoundland, St. John's, New Foundland, A1B 3V6, Canada; Division of Basic Medical Science, Faculty of Medicine, Memorial University of Newfoundland, St. John's, New Foundland, A1B 3V6, Canadaen_US
dc.contributor.affiliationotherSchool of Pharmacy, Memorial University of Newfoundland, St. John's, New Foundland, A1B 3V6, Canadaen_US
dc.contributor.affiliationotherDivision of Basic Medical Science, Faculty of Medicine, Memorial University of Newfoundland, St. John's, New Foundland, A1B 3V6, Canadaen_US
dc.contributor.affiliationotherSchool of Pharmacy, Memorial University of Newfoundland, St. John's, New Foundland, A1B 3V6, Canadaen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid10213374en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41476/1/11095_2004_Article_303522.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1018881904228en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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