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Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor
dc.contributor.authorRaczka, Ewaen_US
dc.contributor.authorBaker, James R. Jr.en_US
dc.contributor.authorMulé, Jamesen_US
dc.contributor.authorMajoros, Istvan J.en_US
dc.contributor.authorMyc, Andrzejen_US
dc.contributor.authorPatri, Anil K.en_US
dc.contributor.authorQuintana, Antonioen_US
dc.contributor.authorThomas, Thommey P.en_US
dc.contributor.authorPiehler, Larsen_US
dc.contributor.authorLee, Inhanen_US
dc.date.accessioned2006-09-08T19:19:07Z
dc.date.available2006-09-08T19:19:07Z
dc.date.issued2002-09en_US
dc.identifier.citationQuintana, Antonio; Raczka, Ewa; Piehler, Lars; Lee, Inhan; Myc, Andrzej; Majoros, Istvan; Patri, Anil K.; Thomas, Thommey; Mulé, James; Baker, James R.; (2002). "Design and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptor." Pharmaceutical Research 19(9): 1310-1316. <http://hdl.handle.net/2027.42/41493>en_US
dc.identifier.issn0724-8741en_US
dc.identifier.issn1573-904Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/41493
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12403067&dopt=citationen_US
dc.description.abstractPurpose . We sought to develop nanoscale drug delivery materials that would allow targeted intracellular delivery while having an imaging capability for tracking uptake of the material. A complex nanodevice was designed and synthesized that targets tumor cells through the folate receptor.en_US
dc.format.extent436735 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPharmacyen_US
dc.subject.otherDendrimeren_US
dc.subject.otherMethotrexateen_US
dc.subject.otherNanotechnologyen_US
dc.subject.otherBiomedical Engineeringen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherChemotherapeutic Molecular Modelingen_US
dc.subject.otherMedical Lawen_US
dc.titleDesign and Function of a Dendrimer-Based Therapeutic Nanodevice Targeted to Tumor Cells Through the Folate Receptoren_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648; Department of Pharmacology, Faculty of Medicine and Odontology, University of the Basque Country, 48940, Leioa (Vizcaya), Spainen_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648en_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan, 48109-0648; Department of Pharmacology, Faculty of Medicine and Odontology, University of the Basque Country, 48940, Leioa (Vizcaya), Spainen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid12403067en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/41493/1/11095_2004_Article_378868.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1020398624602en_US
dc.identifier.sourcePharmaceutical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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