Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model
dc.contributor.author | Fleisher, David | en_US |
dc.contributor.author | Zhou, Simon Yuji | en_US |
dc.contributor.author | Zimmermann, Ellen M. | en_US |
dc.contributor.author | Kesisoglou, Filippos | en_US |
dc.contributor.author | Niemiec, Susan M. | en_US |
dc.contributor.author | Lee, Jordan Wing | en_US |
dc.date.accessioned | 2006-09-08T19:20:09Z | |
dc.date.available | 2006-09-08T19:20:09Z | |
dc.date.issued | 2005-08 | en_US |
dc.identifier.citation | Kesisoglou, Filippos; Zhou, Simon Yuji; Niemiec, Susan; Lee, Jordan Wing; Zimmermann, Ellen M.; Fleisher, David; (2005). "Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model." Pharmaceutical Research 22(8): 1320-1330. <http://hdl.handle.net/2027.42/41509> | en_US |
dc.identifier.issn | 0724-8741 | en_US |
dc.identifier.issn | 1573-904X | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41509 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=16078142&dopt=citation | en_US |
dc.description.abstract | Based on adherence to intestinal mucosa, intralumenally administered liposomal formulations of 5-aminosalicylate (5-ASA) and 6-mercaptopurine (6-MP) were studied for their potential to enhance local drug delivery to intestinal tissue for the treatment of inflammatory bowel disease. | en_US |
dc.format.extent | 377939 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; Springer Science + Business Media, Inc. | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Biomedical Engineering | en_US |
dc.subject.other | Liposomes | en_US |
dc.subject.other | Intestine | en_US |
dc.subject.other | Medical Law | en_US |
dc.subject.other | Drug Delivery | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Inflammatory Bowel Disease | en_US |
dc.subject.other | Absorption | en_US |
dc.subject.other | Pharmacy | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.title | Liposomal Formulations of Inflammatory Bowel Disease Drugs: Local versus Systemic Drug Delivery in a Rat Model | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pharmacy and Pharmacology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pharmaceutical Sciences, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065, USA; Division of Gastroenterology, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan, 48109-0682, USA | en_US |
dc.contributor.affiliationum | Department of Pharmaceutical Sciences, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065, USA | en_US |
dc.contributor.affiliationum | Division of Gastroenterology, Department of Internal Medicine, The University of Michigan, Ann Arbor, Michigan, 48109-0682, USA | en_US |
dc.contributor.affiliationum | Department of Pharmaceutical Sciences, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065, USA | en_US |
dc.contributor.affiliationum | Department of Pharmaceutical Sciences, College of Pharmacy, The University of Michigan, Ann Arbor, Michigan, 48109-1065, USA | en_US |
dc.contributor.affiliationother | Pfizer Global Research and Development, Ann Arbor Laboratories, Ann Arbor, Michigan, 48105, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 16078142 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41509/1/11095_2005_Article_5376.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s11095-005-5376-3 | en_US |
dc.identifier.source | Pharmaceutical Research | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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