Elevated intracranial pressure associated with hypermetabolism in isolated head trauma
dc.contributor.author | Campbell, John A. | en_US |
dc.contributor.author | Bucci, Michael N. | en_US |
dc.contributor.author | Dechert, Ronald E. | en_US |
dc.contributor.author | Bartlett, Robert H. | en_US |
dc.contributor.author | McGillicuddy, John E. | en_US |
dc.contributor.author | Arnoldi, D. K. | en_US |
dc.date.accessioned | 2006-09-08T19:29:21Z | |
dc.date.available | 2006-09-08T19:29:21Z | |
dc.date.issued | 1988-09 | en_US |
dc.identifier.citation | Bucci, M. N.; Dechert, R. E.; Arnoldi, D. K.; Campbell, J.; McGillicuddy, J. E.; Bartlett, R. H.; (1988). "Elevated intracranial pressure associated with hypermetabolism in isolated head trauma." Acta Neurochirurgica 93 (3-4): 133-136. <http://hdl.handle.net/2027.42/41650> | en_US |
dc.identifier.issn | 0001-6268 | en_US |
dc.identifier.issn | 0942-0940 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/41650 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3177029&dopt=citation | en_US |
dc.description.abstract | Both metabolic rate and protein catabolism are known to increase following severe head trauma, but the etiology of this hypermetabolism is unknown. To further investigate the problem, we studied the metabolism of 17 patients with indirect calorimetry who had severe craniocerebral trauma only and who required ICP monitoring for management. Patients were studied daily and immediately after ICP spikes greater than 20 mmHg, prior to treatment with hyperventilation, osmotic diuretics, or barbiturates. Oxygen consumption (VO 2 ) was correlated with ICP. Two groups of patients were identified. Group I patients were treated with hyperventilation and osmotic diuretics while Group II patients additionally received cerebral metabolic depressants. Group I had a significant correlation coefficent between VO 2 and ICP. Significant hypercatabolism early in the post trauma period was demonstrated by increased urine urea nitrogen. Our observations suggest that in patients with craniocerebral trauma, elevated ICP is associated with increased oxygen consumption, protein catabolism and systemic hypermetabolism. Cerebral metabolic depressants blunted increases in VO 2 which were seen with elevated ICP. | en_US |
dc.format.extent | 356517 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Nitrogen Balance | en_US |
dc.subject.other | Interventional Radiology | en_US |
dc.subject.other | Neurology | en_US |
dc.subject.other | Intracranial Pressure | en_US |
dc.subject.other | Oxygen Consumption | en_US |
dc.subject.other | Neurosurgery | en_US |
dc.subject.other | Head Injury | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Neuroradiology | en_US |
dc.subject.other | Minimally Invasive Surgery | en_US |
dc.subject.other | Surgical Orthopedics | en_US |
dc.subject.other | Metabolism | en_US |
dc.title | Elevated intracranial pressure associated with hypermetabolism in isolated head trauma | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA; 2128 Taubman Health Care Center, 1500 East Medical Center Drive, Box 0338, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | Department of Surgery, Sections of Neurosurgery and General Surgery, The University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 3177029 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/41650/1/701_2005_Article_BF01402895.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF01402895 | en_US |
dc.identifier.source | Acta Neurochirurgica | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.