Interactions between T cells and synovial fibroblasts
dc.contributor.author | Yamamura, Yuji | en_US |
dc.contributor.author | Fox, David A. | en_US |
dc.contributor.author | Shelden, Eric | en_US |
dc.date.accessioned | 2006-09-08T20:20:51Z | |
dc.date.available | 2006-09-08T20:20:51Z | |
dc.date.issued | 2000-03 | en_US |
dc.identifier.citation | Yamamura, Y.; Shelden, E.; Fox, D. A.; (2000). "Interactions between T cells and synovial fibroblasts." Modern Rheumatology 10(1): 16-18. <http://hdl.handle.net/2027.42/42445> | en_US |
dc.identifier.issn | 1439-7595 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/42445 | |
dc.description.abstract | T lymphocytes, synovial macrophages, and synovial fibroblasts are the three most abundant cell populations in rheumatoid arthritis synovial tissue, and each is believed to play an important role in the pathogenesis of joint inflammation and destruction. While interactions between T cells and macrophages and between macrophages and fibroblasts have been carefully studied, less attention has been paid to potential interactions between T lymphocytes and synovial fibroblasts. In this review we consider available data which suggests that cell–cell contact between T lymphocytes and synovial fibroblasts may lead to activation of each cell type. This interaction is likely to be significant in the pathophysiology of rheumatoid arthritis. | en_US |
dc.format.extent | 275371 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag Tokyo; The Japan Rheumatism Association and Springer-Verlag Tokyo | en_US |
dc.subject.other | Legacy | en_US |
dc.title | Interactions between T cells and synovial fibroblasts | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Physical Medicine and Rehabilitation | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Division of Rheumatology, Department of Internal Medicine, and Multipurpose Arthritis and Musculoskeletal Diseases Center, University of Michigan, 5520 MSRBI, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-0680, USA Tel.≧+1-734-936-5566; Fax +1-734-763-4151 e-mail: Dfox@umich.edu, US | en_US |
dc.contributor.affiliationum | Department of Anatomy and Cell Biology, University of Michigan, MI, USA, US | en_US |
dc.contributor.affiliationum | Division of Rheumatology, Department of Internal Medicine, and Multipurpose Arthritis and Musculoskeletal Diseases Center, University of Michigan, 5520 MSRBI, 1150 W. Medical Center Drive, Ann Arbor, MI 48109-0680, USA Tel.≧+1-734-936-5566; Fax +1-734-763-4151 e-mail: Dfox@umich.edu, US | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 24383528 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/42445/1/10165-10-1-16_00100016.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s101650070033 | en_US |
dc.identifier.source | Modern Rheumatology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.