Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume
dc.contributor.author | Ennis, Steven R. | en_US |
dc.contributor.author | Sullivan, Stephen E. | en_US |
dc.contributor.author | Harrigan, M. R. | en_US |
dc.contributor.author | Keep, Richard F. | en_US |
dc.date.accessioned | 2006-09-08T20:21:26Z | |
dc.date.available | 2006-09-08T20:21:26Z | |
dc.date.issued | 2003-01 | en_US |
dc.identifier.citation | Harrigan, M. R.; Ennis, S. R.; Sullivan, S. E.; Keep, R. F.; (2003). "Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume." Acta Neurochirurgica 145(1): 49-53. <http://hdl.handle.net/2027.42/42454> | en_US |
dc.identifier.issn | 0001-6268 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/42454 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12545262&dopt=citation | en_US |
dc.description.abstract | Background: Therapeutic cerebral angiogenesis, utilizing angiogenic factors to enhance collateral vessel formation within the central nervous system, is a potential method for cerebral revascularization. A prior dose-response study determined that intracerebroventricular infusion of vascular endothelial growth factor (VEGF) increases vascular density with minimal associated brain edema at a concentration of 5 μg/ml. The purpose of this study was to assess effects of intracerebroventricular infusion of VEGF (5 μg/ml) on cerebral blood flow, infarct volume, and brain edema after ischemia. | en_US |
dc.format.extent | 116256 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; Springer-Verlag Wien | en_US |
dc.subject.other | Keywords: Angiogenesis; Vascular Endothelial Growth Factor; Brain Edema; Cerebral Ischemia. | en_US |
dc.subject.other | Legacy | en_US |
dc.title | Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Surgery and Anesthesiology | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., US | en_US |
dc.contributor.affiliationum | Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., US | en_US |
dc.contributor.affiliationum | Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., US | en_US |
dc.contributor.affiliationum | Department of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., US | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 12545262 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/42454/1/31450049.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s00701-002-1035-1 | en_US |
dc.identifier.source | Acta Neurochirurgica | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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