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Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume
dc.contributor.authorEnnis, Steven R.en_US
dc.contributor.authorSullivan, Stephen E.en_US
dc.contributor.authorHarrigan, M. R.en_US
dc.contributor.authorKeep, Richard F.en_US
dc.date.accessioned2006-09-08T20:21:26Z
dc.date.available2006-09-08T20:21:26Z
dc.date.issued2003-01en_US
dc.identifier.citationHarrigan, M. R.; Ennis, S. R.; Sullivan, S. E.; Keep, R. F.; (2003). "Effects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volume." Acta Neurochirurgica 145(1): 49-53. <http://hdl.handle.net/2027.42/42454>en_US
dc.identifier.issn0001-6268en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/42454
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12545262&dopt=citationen_US
dc.description.abstract  Background: Therapeutic cerebral angiogenesis, utilizing angiogenic factors to enhance collateral vessel formation within the central nervous system, is a potential method for cerebral revascularization. A prior dose-response study determined that intracerebroventricular infusion of vascular endothelial growth factor (VEGF) increases vascular density with minimal associated brain edema at a concentration of 5 μg/ml. The purpose of this study was to assess effects of intracerebroventricular infusion of VEGF (5 μg/ml) on cerebral blood flow, infarct volume, and brain edema after ischemia.en_US
dc.format.extent116256 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlag; Springer-Verlag Wienen_US
dc.subject.otherKeywords: Angiogenesis; Vascular Endothelial Growth Factor; Brain Edema; Cerebral Ischemia.en_US
dc.subject.otherLegacyen_US
dc.titleEffects of intraventricular infusion of vascular endothelial growth factor on cerebral blood flow, edema, and infarct volumeen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelSurgery and Anesthesiologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., USen_US
dc.contributor.affiliationumDepartment of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., USen_US
dc.contributor.affiliationumDepartment of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., USen_US
dc.contributor.affiliationumDepartment of Neurosurgery, University of Michigan Health System, Ann Arbor, Michigan, U.S.A., USen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid12545262en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/42454/1/31450049.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/s00701-002-1035-1en_US
dc.identifier.sourceActa Neurochirurgicaen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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