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Imaging {Au 0 -PAMAM} Gold-dendrimer Nanocomposites in Cells
dc.contributor.authorBielinska, Anna U.en_US
dc.contributor.authorEichman, Jonathan D.en_US
dc.contributor.authorLee, Inhanen_US
dc.contributor.authorBaker, James R. Jr.en_US
dc.contributor.authorBalogh, Lajos P.en_US
dc.date.accessioned2006-09-08T21:17:02Z
dc.date.available2006-09-08T21:17:02Z
dc.date.issued2002-10en_US
dc.identifier.citationBielinska, Anna; Eichman, Jonathan D.; Lee, Inhan; Baker, James R.; Balogh, Lajos; (2002). "Imaging {Au 0 -PAMAM} Gold-dendrimer Nanocomposites in Cells." Journal of Nanoparticle Research 4(5): 395-403. <http://hdl.handle.net/2027.42/43295>en_US
dc.identifier.issn1388-0764en_US
dc.identifier.issn1572-896Xen_US
dc.identifier.urihttps://hdl.handle.net/2027.42/43295
dc.description.abstractDendrimer nanocomposites (DNC) are hybrid nanoparticles formed by the dispersion and immobilization of guest atoms or small clusters in dendritic polymer matrices. They have a great potential in biomedical applications due to their controlled composition, predetermined size, shape and variable surface functionalities. In this work, d =5–25 nm spherical nanoparticles composed of gold and poly(amidoamine) (PAMAM) dendrimers have been selected to demonstrate this nanoparticle based concept. {Au(0) n -PAMAM} gold dendrimer nanocomposites with a well-defined size were synthesized and imaged by transmission electron microscopy both in vitro and in vivo. DNC have also the potential to be used for imaging and drug delivery vehicles either by utilizing bioactive guests or through the incorporation of radioactive isotopes, such as Au-198.en_US
dc.format.extent284934 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers; Springer Science+Business Mediaen_US
dc.subject.otherChemistryen_US
dc.subject.otherInorganic Chemistryen_US
dc.subject.otherPhysical Chemistryen_US
dc.subject.otherCharacterization and Evaluation Materialsen_US
dc.subject.otherApplied Optics, Optoelectronics, Optical Devicesen_US
dc.subject.otherNanocompositesen_US
dc.subject.otherDendrimersen_US
dc.subject.otherImagingen_US
dc.subject.otherGene Transferen_US
dc.subject.otherDrug Deliveryen_US
dc.subject.otherGold/Dendrimer Compositeen_US
dc.titleImaging {Au 0 -PAMAM} Gold-dendrimer Nanocomposites in Cellsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, University of Michigan, 4010 Kresge Research Building II, 200 Zina Pitcher Place, Ann Arbor, MI, 48109-0533, USAen_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, University of Michigan, 4010 Kresge Research Building II, 200 Zina Pitcher Place, Ann Arbor, MI, 48109-0533, USAen_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, University of Michigan, 4010 Kresge Research Building II, 200 Zina Pitcher Place, Ann Arbor, MI, 48109-0533, USAen_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, University of Michigan, 4010 Kresge Research Building II, 200 Zina Pitcher Place, Ann Arbor, MI, 48109-0533, USAen_US
dc.contributor.affiliationumCenter for Biologic Nanotechnology, University of Michigan, 4010 Kresge Research Building II, 200 Zina Pitcher Place, Ann Arbor, MI, 48109-0533, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/43295/1/11051_2004_Article_5101884.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1023/A:1021692006589en_US
dc.identifier.sourceJournal of Nanoparticle Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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