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Quantitative genetic variation in carbonic anhydrase isozymes from tissues of the pig-tailed macaque, Macaca nemestrina
dc.contributor.authorTashian, Richard E.en_US
dc.contributor.authorHeadings, Verle E.en_US
dc.date.accessioned2006-09-11T14:23:37Z
dc.date.available2006-09-11T14:23:37Z
dc.date.issued1971-08en_US
dc.identifier.citationHeadings, Verle E.; Tashian, Richard E.; (1971). "Quantitative genetic variation in carbonic anhydrase isozymes from tissues of the pig-tailed macaque, Macaca nemestrina ." Biochemical Genetics 5(4): 333-345. <http://hdl.handle.net/2027.42/44174>en_US
dc.identifier.issn0006-2928en_US
dc.identifier.issn1573-4927en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/44174
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=4999527&dopt=citationen_US
dc.description.abstractTwo isozymes of carbonic anhydrase (CA I and CA II) were quantified by a radio-immunoassay in 10 different tissues of the pig-tailed macaque. There were clearly differences in relative amounts of the two isozymes, indicating a differential regulation of these two different gene products. An inherited deficiency variant reduced red cell CA I and CA II 5000-fold and 2.7-fold, respectively. In nine other tissues, CA I was reduced from approximately twofold to 110-fold, and CA II was essentially unchanged. The CA I in deficient red cells was immunochemically and electrophoretically identical to common electrophoretic variants of CA I in the pig-tailed macaque and was enzymatically active.en_US
dc.format.extent786853 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherMedical Microbiologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherZoologyen_US
dc.subject.otherHuman Geneticsen_US
dc.titleQuantitative genetic variation in carbonic anhydrase isozymes from tissues of the pig-tailed macaque, Macaca nemestrinaen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan; Medical Genetics Unit, Howard University College of Medicine, Washington, D. C.en_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan Medical School, Ann Arbor, Michiganen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid4999527en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/44174/1/10528_2004_Article_BF00485860.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00485860en_US
dc.identifier.sourceBiochemical Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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