Gastroscopic findings and fecal blood loss following aspirin administration
dc.contributor.author | Fall, Daniel J. | en_US |
dc.contributor.author | Kuiper, Donald H. | en_US |
dc.contributor.author | Overholt, Bergein F. | en_US |
dc.contributor.author | Pollard, H. Marvin | en_US |
dc.date.accessioned | 2006-09-11T14:41:50Z | |
dc.date.available | 2006-09-11T14:41:50Z | |
dc.date.issued | 1969-11 | en_US |
dc.identifier.citation | Kuiper, Donald H.; Overholt, Bergein F.; Fall, Daniel J.; Pollard, H. Marvin; (1969). "Gastroscopic findings and fecal blood loss following aspirin administration." The American Journal of Digestive Diseases 14(11): 761-769. <http://hdl.handle.net/2027.42/44370> | en_US |
dc.identifier.issn | 0002-9211 | en_US |
dc.identifier.issn | 1573-2568 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44370 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5307955&dopt=citation | en_US |
dc.description.abstract | A study of 19 healthy young male subjects (Group 1) was made in which a correlation of aspirin ingestion, fecal blood loss, blood salicylate levels, prothrombin concentrations, and ABO blood groups was sought. An initial 4-day control period was followed by a 4-day test period during which subjects ingested 650 mg aspirin with each meal and at bedtime. Gastroscopy with photography was done on Day 1 and Day 7. Daily fecal blood loss was quantitated using the 51-chromium tagged erythrocyte method. Sixteen patients (Group 2) with a variety of upper gastrointestinal disorders underwent gastroscopy and photography before and after the acute ingestion of aspirin. Results reveal: (1) Aspirin produced petechiae in 4 of 18 subjects and a hemorrhagic gastritis in 1 of 18 in Group 1, (2) aspirin produced no visible lesions in the 16 subjects in Group 2, (3) the mean fecal blood loss during the control period was 0.38±0.35 g/24 hr and rose to 1.54±1.42 g/24 hr (P<0.01) during aspirin ingestion, (4) no correlation between normal or abnormal gastroscopic findings and fecal blood loss was apparent, and (5) no correlation between blood salicylate levels, prothrombin concentrations, and gastroscopic findings or fecal blood loss was detected. | en_US |
dc.format.extent | 455752 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers; Hoeber Medical Division • Harper & Row, Publishers, Incorporated ; Springer Science+Business Media | en_US |
dc.subject.other | Transplant Surgery | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Gastroenterology | en_US |
dc.subject.other | Hepatology | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.title | Gastroscopic findings and fecal blood loss following aspirin administration | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | From the Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Mich | en_US |
dc.contributor.affiliationum | From the Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Mich; Section of Gastroenterology, New York Hospital Cornell Medical Center, New York City | en_US |
dc.contributor.affiliationum | From the Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Mich | en_US |
dc.contributor.affiliationum | From the Department of Internal Medicine, Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Mich | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 5307955 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44370/1/10620_2005_Article_BF02235965.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF02235965 | en_US |
dc.identifier.source | The American Journal of Digestive Diseases | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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