Intestinal infection with Mycobacterium avium in acquired immune deficiency syndrome (AIDS)
dc.contributor.author | Roth, Robert I. | en_US |
dc.contributor.author | Owen, Robert L. | en_US |
dc.contributor.author | Keren, David F. | en_US |
dc.contributor.author | Volberding, Paul A. | en_US |
dc.date.accessioned | 2006-09-11T14:44:27Z | |
dc.date.available | 2006-09-11T14:44:27Z | |
dc.date.issued | 1985-05 | en_US |
dc.identifier.citation | Roth, Robert I.; Owen, Robert L.; Keren, David F.; Volberding, Paul A.; (1985). "Intestinal infection with Mycobacterium avium in acquired immune deficiency syndrome (AIDS)." Digestive Diseases and Sciences 30(5): 497-504. <http://hdl.handle.net/2027.42/44396> | en_US |
dc.identifier.issn | 0163-2116 | en_US |
dc.identifier.issn | 1573-2568 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44396 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2580679&dopt=citation | en_US |
dc.description.abstract | At endoscopy, a 30-year-old man with acquired immune deficiency syndrome (AIDS), Kaposi's sarcoma, diarrhea, and unexplained malabsorption showed erythematous macular duodenal lesions consistent with Whipple's disease by histology and electron microscopy. Symptoms did not respond to tetracycline. Subsequent cultures revealed systemic Mycobacterium avium (M. avium) infection. Tissue from this patient, from patients with Whipple's disease and from a macaque with M. avium were compared. All contained PAS-positive macrophages but M. avium could be distinguished by positive acid-fast stains and a difference in pattern of indirect immunofluorescence staining with bacterial typing antisera. PAS-positive macrophages in the intestinal lamina propria are no longer pathognomonic of Whipple's disease. Ultrastructural and histological similarities between Whipple's disease and M. avium infection suggest that both are manifestations of immune deficits limiting macrophage destruction of particular bacteria after phagocytosis. M. avium must be considered in the differential diagnosis of diarrhea in patients with AIDS and other immunosuppressed conditions. | en_US |
dc.format.extent | 2197058 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Transplant Surgery | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Gastroenterology | en_US |
dc.subject.other | Hepatology | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.title | Intestinal infection with Mycobacterium avium in acquired immune deficiency syndrome (AIDS) | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Medicine and Pathology, University of California, 94121, San Francisco, California; Department of Pathology, University of Michigan, Ann Arbor | en_US |
dc.contributor.affiliationum | Departments of Medicine and Pathology, University of California, 94121, San Francisco, California; Department of Pathology, University of Michigan, Ann Arbor; V.A. Medical Center, 94121, San Francisco, California | en_US |
dc.contributor.affiliationum | Departments of Medicine and Pathology, University of California, 94121, San Francisco, California; Department of Pathology, University of Michigan, Ann Arbor | en_US |
dc.contributor.affiliationum | Departments of Medicine and Pathology, University of California, 94121, San Francisco, California; Department of Pathology, University of Michigan, Ann Arbor | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 2580679 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44396/1/10620_2005_Article_BF01318186.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF01318186 | en_US |
dc.identifier.source | Digestive Diseases and Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.