Campylobacter pylori is not associated with gastroparesis
dc.contributor.author | Barnett, Jeffrey L. | en_US |
dc.contributor.author | Behler, Elizabeth M. | en_US |
dc.contributor.author | Appelman, Henry D. | en_US |
dc.contributor.author | Elta, Grace H. | en_US |
dc.date.accessioned | 2006-09-11T14:45:28Z | |
dc.date.available | 2006-09-11T14:45:28Z | |
dc.date.issued | 1989-11 | en_US |
dc.identifier.citation | Barnett, Jeffrey L.; Behler, Elizabeth M.; Appelman, Henry D.; Elta, Grace H.; (1989). " Campylobacter pylori is not associated with gastroparesis." Digestive Diseases and Sciences 34(11): 1677-1680. <http://hdl.handle.net/2027.42/44408> | en_US |
dc.identifier.issn | 0163-2116 | en_US |
dc.identifier.issn | 1573-2568 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44408 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=2582980&dopt=citation | en_US |
dc.description.abstract | There is a high incidence of Campylobacter pylori in the gastric mucosa of patients with duodenal ulcer, gastric ulcer, and nonulcer dyspepsia. Factors that lead to development of this infection are unknown. We hypothesized that delayed solid-phase gastric emptying, a condition characterized by antral stasis, might predispose to Campylobacter pylori infection. We prospectively studied 51 patients with symptoms of gastroparesis using a solid-phase gastric emptying study and upper endoscopy. Patients were excluded if they had predominant symptoms of epigastric pain or an abnormal endoscopy. Three biopsies were obtained from the antrum and stained with H&E. When any inflammation was present, a Warthin-Starry stain was also performed. These were blindly examined for chronic inflammation, activity, and presence of Campylobacter pylori. Campylobacter pylori was not more common in patients with gastroparesis, documented by delayed gastric emptying, than in patients with a normal emptying study. On the contrary, there was a significantly lower incidence of Campylobacter pylori in those with delayed emptying compared to those with normal emptying (5% vs 31% , P<0.05). Gastritis activity correlated closely with Campylobacter presence. Inactive chronic gastritis with Campylobacter was equally common in those with delayed or normal gastric emptying. Diabetics were no more likely to harbor Campylobacter pylori than nondiabetics (16% vs 25%). The 5% incidence of Campylobacter in the gastroparesis group is less than, but approaches, that previously reported in asymptomatic controls. The 31% incidence of Campylobacter in the group with symptoms of gastroparesis but normal gastric emptying approaches that reported for nonulcer dyspepsia. Our data suggest that gastroparesis does not predispose to Campylobacter pylori infection or histologic chronic gastritis . | en_US |
dc.format.extent | 331294 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Media | en_US |
dc.subject.other | Campylobacter Pylori | en_US |
dc.subject.other | Hepatology | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Gastroenterology | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Transplant Surgery | en_US |
dc.subject.other | Biochemistry, General | en_US |
dc.subject.other | Gastroparesis | en_US |
dc.subject.other | Gastritis | en_US |
dc.subject.other | Diabetes Mellitus | en_US |
dc.title | Campylobacter pylori is not associated with gastroparesis | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Internal Medicine and Specialties | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Departments of Internal Medicine and Pathology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Departments of Internal Medicine and Pathology, University of Michigan, Ann Arbor, Michigan; Gastroenterology, 3912 Taubman Center, University of Michigan Hospital, 48109-0362, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Departments of Internal Medicine and Pathology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Departments of Internal Medicine and Pathology, University of Michigan, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 2582980 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44408/1/10620_2005_Article_BF01540043.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF01540043 | en_US |
dc.identifier.source | Digestive Diseases and Sciences | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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