Cytogenetics of human malignant melanoma
dc.contributor.author | Trent, Jeffrey M. | en_US |
dc.date.accessioned | 2006-09-11T14:53:57Z | |
dc.date.available | 2006-09-11T14:53:57Z | |
dc.date.issued | 1991-06 | en_US |
dc.identifier.citation | Trent, Jeffrey M.; (1991). "Cytogenetics of human malignant melanoma." CANCER AND METASTASIS REVIEW 10(2): 103-113. <http://hdl.handle.net/2027.42/44500> | en_US |
dc.identifier.issn | 0167-7659 | en_US |
dc.identifier.issn | 1573-7233 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44500 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1873851&dopt=citation | en_US |
dc.description.abstract | There has been a tremendous recent resurgence of interest in examining chromosomal abnormalities in human cancers (particularly solid tumors). This interest has been stimulated by the molecular examination of recurring chromosome abnormalities, and the recognition that they may pinpoint the location of growth regulatory sequences (e.g. cellular oncogenes). This finding coupled with the clear recognition that specific chromosome abnormalities can also have important diagnostic and prognostic implications, have caused this avenue of research to expand at a significant rate. The following brief review will summarize the current state of knowledge regarding recurring chromosome abnormalities in human malignant melanoma. A discussion of chromosome changes in pre-malignant skin lesions, primary melanoma, and metastatic melanoma is described. Brief descriptions of the potential clinical utility, and biologic relevance of chromosome abnormalities in this disorder are also discussed. | en_US |
dc.format.extent | 858177 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers; Springer Science+Business Media | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Cancer Research | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Cytogenetics | en_US |
dc.subject.other | Malignant Melanoma | en_US |
dc.title | Cytogenetics of human malignant melanoma | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Radiation Oncology and Human Genetics, University of Michigan, 1150 W. Medical Center Drive, 48109-0668, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1873851 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44500/1/10555_2004_Article_BF00049408.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00049408 | en_US |
dc.identifier.source | CANCER AND METASTASIS REVIEW | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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