Racial differences in lung cancer
dc.contributor.author | Gadgeel, Shirish M. | en_US |
dc.contributor.author | Kalemkerian, Gregory P. | en_US |
dc.date.accessioned | 2006-09-11T14:56:57Z | |
dc.date.available | 2006-09-11T14:56:57Z | |
dc.date.issued | 2003-03 | en_US |
dc.identifier.citation | Gadgeel, Shirish M.; Kalemkerian, Gregory P.; (2003). "Racial differences in lung cancer." Cancer and Metastasis Reviews 22(1): 39-46. <http://hdl.handle.net/2027.42/44537> | en_US |
dc.identifier.issn | 0167-7659 | en_US |
dc.identifier.issn | 1573-7233 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/44537 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=12716035&dopt=citation | en_US |
dc.description.abstract | Although race, in and of itself, is not a relevant biologic variable, racial differences in disease characteristics and outcomes have been reported in many malignancies, including lung cancer. The lung cancer incidence rate in blacks has been consistently higher than that in whites for many years. This racial disparity is seen primarily in men and is significantly greater in younger age groups. The reason for higher lung cancer incidence rates in blacks remains unclear, but racial differences in smoking habits, socioeconomic variables, and the metabolism of tobacco carcinogens may all play an important role. Blacks are also more likely than whites to present with squamous cell carcinoma and with advanced-stage disease. A significant racial difference in survival rates has developed over the past 30 years, with a poorer prognosis noted in black patients, particularly those with local- and regional-stage disease. This disparity appears to be due to a lack of improvement in the survival of black patients with lung cancer, but the biological and/or societal basis for racial variations in survival have not been determined. In summary, significant racial differences exist in lung cancer incidence and survival rates. Further research is required to determine the factors responsible for these differences and to develop effective preventative and therapeutic interventions that will impact favorably on the incidence and prognosis of this disease. | en_US |
dc.format.extent | 240579 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Kluwer Academic Publishers; Springer Science+Business Media | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.subject.other | Cancer Research | en_US |
dc.subject.other | Oncology | en_US |
dc.subject.other | Lung Cancer | en_US |
dc.subject.other | Race | en_US |
dc.subject.other | African American | en_US |
dc.subject.other | Epidemiology | en_US |
dc.subject.other | Incidence | en_US |
dc.subject.other | Survival | en_US |
dc.title | Racial differences in lung cancer | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Oncology and Hematology | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Medicine, University of Michigan, Ann Arbor, MI | en_US |
dc.contributor.affiliationother | Department of Medicine, Wayne State University, Karmanos Cancer Institute, Detroit, MI | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 12716035 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/44537/1/10555_2004_Article_5111825.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1023/A:1022207917249 | en_US |
dc.identifier.source | Cancer and Metastasis Reviews | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.