Minimal Contact Intervention with Autologous BMT Patients: Impact on QOL and Emotional Distress

Abstract

Bone marrow transplantation (BMT) is often a last treatment option for individuals who have experienced relapse or treatment failure and is often accompanied by increased levels of distress and reductions in quality of life (QOL). Despite this, few studies have been designed to improve post-BMT QOL and reduce distress. The current study examined the course of distress and QOL in 26 autologus BMT patients and the effect on distress and QOL of providing a minimal contact workbook intervention. Physical well-being decreased following the BMT, but increased at 2- and 6-month follow-up assessments, and distress did not significantly vary over the course of the study for patients in the standard care and workbook intervention groups. Examination of the reasons for the lack of group differences revealed that approximately half of the individuals randomized to the workbook intervention did not look at the material; with those that did reporting higher QOL, decreased anxiety, more adaptive coping, and decreased religiosity. The results argue for the importance of targeting patients at need prior to the transplant procedure, triaging them based on specific characteristics, and providing treatments that match these characteristics.