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Subcellular distributions of calcium/calmodulin-stimulated and guanine nucleotide-regulated adenylate cyclase activities in the cerebral cortex
dc.contributor.authorUeda, Tetsufumien_US
dc.contributor.authorBissen, Shirley T.en_US
dc.date.accessioned2006-09-11T16:01:04Z
dc.date.available2006-09-11T16:01:04Z
dc.date.issued1986-03en_US
dc.identifier.citationBissen, Shirley T.; Ueda, Tetsufumi; (1986). "Subcellular distributions of calcium/calmodulin-stimulated and guanine nucleotide-regulated adenylate cyclase activities in the cerebral cortex." Neurochemical Research 11(3): 453-463. <http://hdl.handle.net/2027.42/45402>en_US
dc.identifier.issn1573-6903en_US
dc.identifier.issn0364-3190en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/45402
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3703110&dopt=citationen_US
dc.description.abstractThe subcellular distribution of Ca 2+ /calmodulin-stimulated adenylate cyclase activity was studied in comparison with that of guanine nucleotide-stimulated cyclase activity. The distributions of these activities were similar among the crude fractions but differed among the purified subsynaptosomal fractions. The specific activity of Ca 2+ /calmodulin-stimulated cyclase was highest in a light synaptic membrane fraction, which has few, if any, postsynaptic densities, whereas that of guanine nucleotide-stimulated cyclase was highest in a heavier synaptic membrane fraction rich in postsynaptic densities. These results suggest that the Ca 2+ /calmodulin-stimulated cyclase has, at least in part, a different cellular or subcellular location than the guanine nucleotide-stimulated cyclase.en_US
dc.format.extent537369 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherNeurosciencesen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherNeurologyen_US
dc.subject.otherBiochemistry, Generalen_US
dc.titleSubcellular distributions of calcium/calmodulin-stimulated and guanine nucleotide-regulated adenylate cyclase activities in the cerebral cortexen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPublic Healthen_US
dc.subject.hlbsecondlevelPsychologyen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelInternal Medicine and Specialtiesen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelSocial Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan, 48109, Ann Arbor, Michigan; Department of Zoology, University of California, 94720, Berkeley, CAen_US
dc.contributor.affiliationumDepartment of Pharmacology, The University of Michigan, 48109, Ann Arbor, Michigan; Department of Psychiatry, The University of Michigan, 48109, Ann Arbor, Michigan; Mental Health Research Institute, The University of Michigan, 48109, Ann Arbor, Michiganen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid3703110en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/45402/1/11064_2004_Article_BF00965018.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00965018en_US
dc.identifier.sourceNeurochemical Researchen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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