View Item 

Show simple item record

Further studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibody

dc.contributor.authorMacKenzie, Douglasen_US
dc.contributor.authorLehman, David W.en_US
dc.contributor.authorCarey, Thomas E.en_US
dc.contributor.authorJones, Carolen_US
dc.contributor.authorKimmel, Kathryn A.en_US
dc.contributor.authorMiller, York E.en_US
dc.date.accessioned2006-09-11T16:12:00Z
dc.date.available2006-09-11T16:12:00Z
dc.date.issued1983-07en_US
dc.identifier.citationJones, Carol; Kimmel, Kathryn A.; Carey, Thomas E.; Miller, York E.; Lehman, David W.; MacKenzie, Douglas; (1983). "Further studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibody." Somatic Cell Genetics 9(4): 489-496. <http://hdl.handle.net/2027.42/45556>en_US
dc.identifier.issn1572-9931en_US
dc.identifier.issn0098-0366en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/45556
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=6623310&dopt=citationen_US
dc.description.abstractA monoclonal antibody has been obtained that recognizes an antigen encoded by human chromosome 11. We present evidence that this monoclonal antibody recognizes the same or a similar antigenic activity as that previously called a 1 . Genetic information necessary for a 1 expression and recognition by the monoclonal antibody both map to 11p13 → 11pter. Mutants that have lost a 1 are no longer recognized by the monoclonal antibody. The macroglycolipid fraction of human erythrocyte membranes which contains the a 1 antigenic activity is able to convert antigen-negative Chinese hamster ovary cells into cells which are killed by the monoclonal antibody plus complement.en_US
dc.format.extent814339 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherKluwer Academic Publishers-Plenum Publishers; Plenum Publishing Corporation ; Springer Science+Business Mediaen_US
dc.subject.otherPlant Sciencesen_US
dc.subject.otherHuman Geneticsen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherBiochemistry, Generalen_US
dc.subject.otherAnimal Anatomy / Morphology / Histologyen_US
dc.titleFurther studies on a hybrid cell-surface antigen associated with human chromosome 11 using a monoclonal antibodyen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Microbiology and Immunology, University of Michigan, 48109, Ann Arbor, Michiganen_US
dc.contributor.affiliationumDepartment of Microbiology and Immunology, University of Michigan, 48109, Ann Arbor, Michigan; The Cancer Research Laboratory in the Department of Otorhinolaryngology, University of Michigan, 48109, Ann Arbor, Michiganen_US
dc.contributor.affiliationotherEleanor Roosevelt Institute for Cancer Research, Inc., University of Colorado Health Sciences Center, 80262, Denver, Colorado; Department of Biochemistry, Biophysics and Genetics, University of Colorado Health Sciences Center, 80262, Denver, Coloradoen_US
dc.contributor.affiliationotherEleanor Roosevelt Institute for Cancer Research, Inc., University of Colorado Health Sciences Center, 80262, Denver, Colorado; Department of Medicine, University of Colorado Health Sciences Center, 80262, Denver, Coloradoen_US
dc.contributor.affiliationotherEleanor Roosevelt Institute for Cancer Research, Inc., University of Colorado Health Sciences Center, 80262, Denver, Coloradoen_US
dc.contributor.affiliationotherEleanor Roosevelt Institute for Cancer Research, Inc., University of Colorado Health Sciences Center, 80262, Denver, Coloradoen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid6623310en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/45556/1/11188_2005_Article_BF01543049.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF01543049en_US
dc.identifier.sourceSomatic Cell Geneticsen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
11188_2005_Article_BF01543049.pdf
Size:
795.2KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.