Brassinosteroid Signal Transduction: A Mix of Conservation and Novelty
dc.contributor.author | Li, Jianming | en_US |
dc.contributor.author | Peng, Peng | en_US |
dc.date.accessioned | 2006-09-11T17:10:06Z | |
dc.date.available | 2006-09-11T17:10:06Z | |
dc.date.issued | 2003-12 | en_US |
dc.identifier.citation | Peng, Peng; Li, Jianming; (2003). "Brassinosteroid Signal Transduction: A Mix of Conservation and Novelty." Journal of Plant Growth Regulation 22(4): 298-312. <http://hdl.handle.net/2027.42/45932> | en_US |
dc.identifier.issn | 1435-8107 | en_US |
dc.identifier.issn | 0721-7595 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/45932 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=14676969&dopt=citation | en_US |
dc.description.abstract | Brassinosteroids (BRs) are a unique class of plant steroids that are structurally similar to animal steroid hormones and play important roles in plant growth and development. Unlike the animal steroids, which bind to classical intracellular steroid receptors that directly modulate gene activities after translocation into the nucleus, the plant steroids rely on transmembrane receptor kinases to activate a phosphorylation cascade to regulate gene expression. Recent genetic and biochemical studies have identified several critical BR signaling components and revealed a striking mechanistic similarity between the plant steroid signaling pathway and several well-studied animal signaling cascades involving a receptor kinase and glycogen synthase kinase 3 (GSK3). A working model for BR signal transduction proposes that BR initiates its signaling pathway by promoting heterodimerization of two transmembrane receptor-like kinases at the cell surface, leading to inhibition of a GSK3 kinase and subsequent stabilization and nuclear accumulation of two GSK3 substrates that regulate BR-responsive genes. Such a simple model provides a framework for continued investigation of molecular mechanism(s) of plant steroid signaling. | en_US |
dc.format.extent | 406528 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | GSK3 | en_US |
dc.subject.other | Receptor Heterodimerization | en_US |
dc.subject.other | Arabidopsis | en_US |
dc.subject.other | Philosophy | en_US |
dc.subject.other | Brassinosteroid | en_US |
dc.subject.other | Leucine-rich-Repeat Receptor-like Kinase | en_US |
dc.subject.other | Steroid Signaling | en_US |
dc.title | Brassinosteroid Signal Transduction: A Mix of Conservation and Novelty | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationum | Department of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 14676969 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/45932/1/344_2003_Article_59.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/s00344-003-0059-y | en_US |
dc.identifier.source | Journal of Plant Growth Regulation | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
Files in this item
Remediation of Harmful Language
The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.
Accessibility
If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.