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Role of oxygen radicals in tourniquet-related ischemia-reperfusion injury of human patients
dc.contributor.authorTrentz, O.en_US
dc.contributor.authorWard, Peter A.en_US
dc.contributor.authorFriedl, Hans P.en_US
dc.contributor.authorTill, Gerd O.en_US
dc.date.accessioned2006-09-11T17:14:36Z
dc.date.available2006-09-11T17:14:36Z
dc.date.issued1991-12en_US
dc.identifier.citationFriedl, H. P.; Till, G. O.; Trentz, O.; Ward, P. A.; (1991). "Role of oxygen radicals in tourniquet-related ischemia-reperfusion injury of human patients." Klinische Wochenschrift 69 (21-23): 1109-1112. <http://hdl.handle.net/2027.42/45987>en_US
dc.identifier.issn1432-1440en_US
dc.identifier.issn0023-2173en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/45987
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1798287&dopt=citationen_US
dc.description.abstractIn the current study we evaluated effluent blood from extremities of human patients undergoing reconstructive surgical treatment which is routinely accompanied by upper extremity exsanguination and application of a tourniquet. Following tourniquet release (reperfusion), there were immediate increases in the plasma levels of xanthine oxidase activity, uric acid, and histamine. Xanthine dehydrogenase activity was not detectable. Plasma also contained products consistent with the formation of oxygen-derived free radicals, namely hemoglobin and fluorescent compounds. Our data indicate in humans that ischemia-reperfusion events are associated with the appearance of xanthine oxidase activity and it's products in the plasma effluent.en_US
dc.format.extent401125 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherXanthine Oxidaseen_US
dc.subject.otherMolecular Medicineen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherInternal Medicineen_US
dc.subject.otherTourniqueten_US
dc.subject.otherReperfusion Injuryen_US
dc.titleRole of oxygen radicals in tourniquet-related ischemia-reperfusion injury of human patientsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelMedicine (General)en_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arboren_US
dc.contributor.affiliationumDepartment of Pathology, University of Michigan Medical School, Ann Arboren_US
dc.contributor.affiliationotherDepartement Chirurgie, Klinik für Unfallchirurgie, Universitätsspital Zürich, Schweizen_US
dc.contributor.affiliationotherDepartement Chirurgie, Klinik für Unfallchirurgie, Universitätsspital Zürich, Schweizen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid1798287en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/45987/1/109_2005_Article_BF01645168.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF01645168en_US
dc.identifier.sourceKlinische Wochenschriften_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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