View Item 

Show simple item record

Psychotropic drug influences on brain acetylcholine utilization
dc.contributor.authorDomino, Edward F.en_US
dc.contributor.authorWilson, Ann E.en_US
dc.date.accessioned2006-09-11T17:42:58Z
dc.date.available2006-09-11T17:42:58Z
dc.date.issued1972-12en_US
dc.identifier.citationDomino, Edward F.; Wilson, Ann E.; (1972). "Psychotropic drug influences on brain acetylcholine utilization." Psychopharmacologia 25(4): 291-298. <http://hdl.handle.net/2027.42/46382>en_US
dc.identifier.issn0033-3158en_US
dc.identifier.issn1432-2072en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/46382
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=5051143&dopt=citationen_US
dc.description.abstractThe cholinergic antisynthesis agent HC-3 was given intraventricularly to young male rats 20–30 days old to deplete brain acetylcholine (ACh). The rate of HC-3 induced depletion of ACh was used as an index of ACh utilization. Total brain ACh was determined following various doses of chlordiazepoxide, pentobarbital, chlorpromazine, methotrimeprazine, imipramine, morphine, d -amphetamine, scopolamine, LSD-25, and phencyclidine given i.p. alone and after intraventricular administration of HC-3. It was found that psychotropic drugs have marked differential effects on the rate of HC-3 induced ACh depletion.en_US
dc.format.extent416991 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherLSD-25en_US
dc.subject.otherMorphineen_US
dc.subject.otherPsychiatryen_US
dc.subject.otherD -Amphetamineen_US
dc.subject.otherPsychotropic Drugsen_US
dc.subject.otherChlorpromazineen_US
dc.subject.otherPheneyclidineen_US
dc.subject.otherAcetylcholineen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherChlordiazepoxideen_US
dc.subject.otherImipramineen_US
dc.subject.otherMethotrimeprazineen_US
dc.subject.otherScopolamineen_US
dc.titlePsychotropic drug influences on brain acetylcholine utilizationen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMichigan Neuropsychopharmacology Research Program, Department of Pharmacology, University of Michigan, Ann Arbor; Lafayette Clinic, Detroit, USAen_US
dc.contributor.affiliationumMichigan Neuropsychopharmacology Research Program, Department of Pharmacology, University of Michigan, Ann Arbor; Lafayette Clinic, Detroit, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid5051143en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/46382/1/213_2004_Article_BF00421968.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00421968en_US
dc.identifier.sourcePsychopharmacologiaen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


Files in this item

Name:
213_2004_Article_BF00421968.pdf
Size:
407.2KB
Format:
PDF
View/Open

Show simple item record

Remediation of Harmful Language

The University of Michigan Library aims to describe library materials in a way that respects the people and communities who create, use, and are represented in our collections. Report harmful or offensive language in catalog records, finding aids, or elsewhere in our collections anonymously through our metadata feedback form. More information at Remediation of Harmful Language.

Accessibility

If you are unable to use this file in its current format, please select the Contact Us link and we can modify it to make it more accessible to you.