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Intracranial reward after Lilly 110140 (fluoxetine HCl): Evidence for an inhibitory role for serotonin

dc.contributor.authorCarroll, Bernard J.en_US
dc.contributor.authorKatz, Richard J.en_US
dc.date.accessioned2006-09-11T17:44:07Z
dc.date.available2006-09-11T17:44:07Z
dc.date.issued1977-01en_US
dc.identifier.citationKatz, R. J.; Carroll, B. J.; (1977). "Intracranial reward after Lilly 110140(fluoxetine HCl): Evidence for an inhibitory role for serotonin." Psychopharmacology 51 (2): 189-193. <http://hdl.handle.net/2027.42/46398>en_US
dc.identifier.issn0033-3158en_US
dc.identifier.issn1432-2072en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/46398
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=402672&dopt=citationen_US
dc.description.abstractThe 5-hydroxytryptamine (5-HT, serotonin) specific presynaptic reuptake inhibitor Lilly 110140 (fluoxetine hydrochloride) was injected systemically in rats trained to bar-press for rewarding stimulation to the caudal portion ofthe medial forebrain bundle. Rates of self stimulation were reduced in proportion to drug dosage, and these reductions were partially reversible by methysergide. These findings are consistent with previous reports suggesting an inhibitory role for 5-HT in self stimulation.en_US
dc.format.extent478612 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherFluoxetineen_US
dc.subject.otherMethysergideen_US
dc.subject.otherSelf Stimulationen_US
dc.subject.otherSerotoninen_US
dc.subject.otherPsychiatryen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherBrain Stimulationen_US
dc.subject.other5-Hydroxytryptamineen_US
dc.titleIntracranial reward after Lilly 110140 (fluoxetine HCl): Evidence for an inhibitory role for serotoninen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumMental Health Research Institute, Department of Psychiatry, University of Michigan, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumMental Health Research Institute, Department of Psychiatry, University of Michigan, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid402672en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/46398/1/213_2004_Article_BF00431739.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00431739en_US
dc.identifier.sourcePsychopharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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