Facilitation of opiate-and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine
dc.contributor.author | Katz, Richard J. | en_US |
dc.contributor.author | Schmaltz, Kristine | en_US |
dc.date.accessioned | 2006-09-11T17:44:58Z | |
dc.date.available | 2006-09-11T17:44:58Z | |
dc.date.issued | 1979-01 | en_US |
dc.identifier.citation | Katz, R. J.; Schmaltz, Kristine; (1979). "Facilitation of opiate-and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine." Psychopharmacology 65(1): 65-68. <http://hdl.handle.net/2027.42/46410> | en_US |
dc.identifier.issn | 1432-2072 | en_US |
dc.identifier.issn | 0033-3158 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/46410 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=116291&dopt=citation | en_US |
dc.description.abstract | In the first experiment, adult male Swiss-Webster mice were systemically injected with a standard dose of morphine. Compared to the influence of vehicle, the motor activity of morphine-injected mice was increased. Neither phenytoin sodium nor carbamazepine alone facilitated motor activity, but pretreatment with both drugs further facilitated the increased motor activity produced by morphine. In a second experiment, mice were injected centrally with a long-acting analog of leu-enkephalin. It also increased motor activity in comparison with vehicle. Again, both phenytoin sodium and carbamazepine further facilitated this response. Both experiments suggest a facilitatory interaction between some aspects of these anticonvulsants and opiate-induced motor activity. | en_US |
dc.format.extent | 471872 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Enkephalin | en_US |
dc.subject.other | Motor | en_US |
dc.subject.other | Pharmacology/Toxicology | en_US |
dc.subject.other | Anticonvulsant Drugs | en_US |
dc.subject.other | Morphine | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Psychiatry | en_US |
dc.subject.other | Carbamazepine | en_US |
dc.subject.other | Opiate | en_US |
dc.subject.other | Phenytoin Sodium | en_US |
dc.subject.other | Psychomotor Activity | en_US |
dc.title | Facilitation of opiate-and enkephalin-induced motor activity in the mouse by phenytoin sodium and carbamazepine | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Psychiatry | en_US |
dc.subject.hlbsecondlevel | Neurosciences | en_US |
dc.subject.hlbsecondlevel | Chemistry | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, Department of Psychiatry, University of Michigan Medical Center, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationum | Mental Health Research Institute, Department of Psychiatry, University of Michigan Medical Center, 48109, Ann Arbor, MI, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 116291 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/46410/1/213_2004_Article_BF00491980.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00491980 | en_US |
dc.identifier.source | Psychopharmacology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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