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Opioid but not nonopioid stress-induced analgesia is enhanced following prenatal exposure to ethanol
dc.contributor.authorBranch, B. J.en_US
dc.contributor.authorLiebeskind, John C.en_US
dc.contributor.authorNelson, L. R.en_US
dc.contributor.authorTaylor, A. N.en_US
dc.contributor.authorLewis, James W.en_US
dc.date.accessioned2006-09-11T17:46:45Z
dc.date.available2006-09-11T17:46:45Z
dc.date.issued1985-01en_US
dc.identifier.citationNelson, L. R.; Taylor, A. N.; Lewis, J. W.; Branch, B. J.; Liebeskind, J. C.; (1985). "Opioid but not nonopioid stress-induced analgesia is enhanced following prenatal exposure to ethanol." Psychopharmacology 85(1): 92-96. <http://hdl.handle.net/2027.42/46435>en_US
dc.identifier.issn1432-2072en_US
dc.identifier.issn0033-3158en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/46435
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=3920703&dopt=citationen_US
dc.description.abstractTwo neurochemically distinct forms of stress-induced analgesia were examined in adult rats following prenatal ethanol exposure. Rats were exposed to ethanol during the last 2 weeks of gestation through a liquid diet presented to the dams. Analgesia testing was conducted when the offspring were 150–210 days of age. Two forms of footshock stress were administered; one that resulted in a naloxone-sensitive (opioid-mediated) analgesia and one that resulted in a naloxone-insensitive (nonopioid) form of analgesia. Rats prenatally exposed to ethanol demonstrated significantly enhanced opioid-mediated analgesia, but unaltered nonpoioid analgesia compared to controls. These results confirm previous findings that prenatal exposure to ethanol leads to long-term alterations in responding to some, but not all forms of stress. The possibility that prenatal exposure to ethanol leads to perturbations in the endogenous opioid systems is discussed.en_US
dc.format.extent467296 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherStress-induced Analgesiaen_US
dc.subject.otherFetal Alcohol Syndromeen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherPsychiatryen_US
dc.subject.otherEndogenous Opioid Peptidesen_US
dc.subject.otherEthanolen_US
dc.subject.otherPrenatal Ethanol Exposureen_US
dc.titleOpioid but not nonopioid stress-induced analgesia is enhanced following prenatal exposure to ethanolen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPsychiatryen_US
dc.subject.hlbsecondlevelNeurosciencesen_US
dc.subject.hlbsecondlevelChemistryen_US
dc.subject.hlbsecondlevelBiological Chemistryen_US
dc.subject.hlbtoplevelScienceen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Psychology, UCLA, 405 Hilgard Avenue, 90024, Los Angeles, CA, USA; Department of Anatomy, University of California, 90024, Los Angeles, CA, USA; Brain Research Institute, University of California, 90024, Los Angeles, CA, USA; Brentwood Division, West Los Angeles VA Medical Center, 90024, Los Angeles, CA, USA; Mental Health Research Institute, University of Michigan, 48109, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherDepartment of Psychology, UCLA, 405 Hilgard Avenue, 90024, Los Angeles, CA, USA; Department of Anatomy, University of California, 90024, Los Angeles, CA, USA; Brain Research Institute, University of California, 90024, Los Angeles, CA, USA; Brentwood Division, West Los Angeles VA Medical Center, 90024, Los Angeles, CA, USAen_US
dc.contributor.affiliationotherDepartment of Psychology, UCLA, 405 Hilgard Avenue, 90024, Los Angeles, CA, USA; Department of Anatomy, University of California, 90024, Los Angeles, CA, USA; Brain Research Institute, University of California, 90024, Los Angeles, CA, USA; Brentwood Division, West Los Angeles VA Medical Center, 90024, Los Angeles, CA, USAen_US
dc.contributor.affiliationotherDepartment of Psychology, UCLA, 405 Hilgard Avenue, 90024, Los Angeles, CA, USA; Department of Anatomy, University of California, 90024, Los Angeles, CA, USA; Brain Research Institute, University of California, 90024, Los Angeles, CA, USA; Brentwood Division, West Los Angeles VA Medical Center, 90024, Los Angeles, CA, USAen_US
dc.contributor.affiliationotherDepartment of Psychology, UCLA, 405 Hilgard Avenue, 90024, Los Angeles, CA, USA; Department of Anatomy, University of California, 90024, Los Angeles, CA, USA; Brain Research Institute, University of California, 90024, Los Angeles, CA, USA; Brentwood Division, West Los Angeles VA Medical Center, 90024, Los Angeles, CA, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid3920703en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/46435/1/213_2004_Article_BF00427329.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00427329en_US
dc.identifier.sourcePsychopharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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