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Recovery cycle of the Hoffmann reflex of tobacco smokers and nonsmokers: relationship to plasma nicotine and cotinine levels
dc.contributor.authorKadoya, C.en_US
dc.contributor.authorMatsuoka, S.en_US
dc.contributor.authorDomino, Edward F.en_US
dc.date.accessioned2006-09-11T18:01:45Z
dc.date.available2006-09-11T18:01:45Z
dc.date.issued1994-07en_US
dc.identifier.citationDomino, E. F.; Kadoya, C.; Matsuoka, S.; (1994). "Recovery cycle of the Hoffmann reflex of tobacco smokers and nonsmokers: relationship to plasma nicotine and cotinine levels." European Journal of Clinical Pharmacology 46(6): 527-532. <http://hdl.handle.net/2027.42/46642>en_US
dc.identifier.issn0031-6970en_US
dc.identifier.issn1432-1041en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/46642
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=7995320&dopt=citationen_US
dc.description.abstractTen normal adult tobacco smokers and 10 non-smoking volunteers 20–31 years of age were the subjects of this study. The tobacco smokers all had a history of daily tobacco smoking. They were asked to stop smoking for 12 hours prior to testing. The Hoffmann (H) reflex and its recovery cycle were measured on different days before and just after smoking one nonfiltered 0 mg, low (0.27 mg), or high (2.16 mg) nicotine containing cigarette in a randomized order. Blood samples were drawn immediately after the H reflex recordings in the tobacco smokers. The blood samples were centrifuged, the plasma removed, frozen, and later assayed for nicotine and cotinine levels.en_US
dc.format.extent639725 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherPlasma Cotinineen_US
dc.subject.otherRecovery Cycleen_US
dc.subject.otherPlasma Nicotineen_US
dc.subject.otherHoffmann Reflexen_US
dc.subject.otherBiomedicineen_US
dc.subject.otherPharmacology/Toxicologyen_US
dc.subject.otherTobacco Smokingen_US
dc.titleRecovery cycle of the Hoffmann reflex of tobacco smokers and nonsmokers: relationship to plasma nicotine and cotinine levelsen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelPharmacy and Pharmacologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Department of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japanen_US
dc.contributor.affiliationumDepartment of Pharmacology, University of Michigan, Ann Arbor, Michigan, USA; Department of Pharmacology, University of Michigan, M6414 Medical Science Bldg. I, 48109-0626, Ann Arbor, MI, USAen_US
dc.contributor.affiliationotherDepartment of Neurosurgery, University of Occupational and Environmental Health, Kitakyushu, Japanen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid7995320en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/46642/1/228_2004_Article_BF00196110.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00196110en_US
dc.identifier.sourceEuropean Journal of Clinical Pharmacologyen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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