Partial characterization of Ia antigens from murine lymphoid cells
dc.contributor.author | Vitetta, Ellen S. | en_US |
dc.contributor.author | Klein, Jan | en_US |
dc.contributor.author | Uhr, Jonathan W. | en_US |
dc.date.accessioned | 2006-09-11T18:07:58Z | |
dc.date.available | 2006-09-11T18:07:58Z | |
dc.date.issued | 1974-12 | en_US |
dc.identifier.citation | Vitetta, Ellen S.; Klein, Jan; Uhr, Jonathan W.; (1974). "Partial characterization of Ia antigens from murine lymphoid cells." Immunogenetics 1(1): 82-90. <http://hdl.handle.net/2027.42/46728> | en_US |
dc.identifier.issn | 1432-1211 | en_US |
dc.identifier.issn | 0093-7711 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/46728 | |
dc.description.abstract | Congenic anti-Ia antisera were used to bind radiolabelled Ia antigens from cells of various strains of mice of known H-2 haplotype. The results indicate that Ia antigens are proteins of molecular weight 30,000 to 35,000 daltons. The Ia antigens are distinct from known H-2 antigens as judged by independent immunoprecipitation as well as by molecular weight. Ia antigens are synthesized by, and are present on the surface of lymphoid cells as evidenced by incorporation studies using 3 H-leucine and enzymatic radioiodination of cells, respectively. Tissue distribution of cell surface Ia suggests that Ia antigens are on B cells. Ia antigens were detected in the incubation media of 3 H-leucine labeled splenocytes suggesting that antigens may be secreted. | en_US |
dc.format.extent | 438952 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag; Springer-Verlag New York Inc. | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Immunology | en_US |
dc.subject.other | Allergology | en_US |
dc.title | Partial characterization of Ia antigens from murine lymphoid cells | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Public Health | en_US |
dc.subject.hlbsecondlevel | Biological Chemistry | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Microbiology, University of Texas, Southwestern Medical School, 75235, Dallas, Texas; Irvington House Institute and Department of Microbiology, N.Y.U. School of Medicine, 10016, New York, N.Y.; Departments of Human Genetics and Oral Biology, Schools of Dentistry and Medicine, University of Michigan, 48104, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Microbiology, University of Texas, Southwestern Medical School, 75235, Dallas, Texas; Irvington House Institute and Department of Microbiology, N.Y.U. School of Medicine, 10016, New York, N.Y.; Departments of Human Genetics and Oral Biology, Schools of Dentistry and Medicine, University of Michigan, 48104, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationum | Department of Microbiology, University of Texas, Southwestern Medical School, 75235, Dallas, Texas; Irvington House Institute and Department of Microbiology, N.Y.U. School of Medicine, 10016, New York, N.Y.; Departments of Human Genetics and Oral Biology, Schools of Dentistry and Medicine, University of Michigan, 48104, Ann Arbor, Michigan | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/46728/1/251_2005_Article_BF01564048.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF01564048 | en_US |
dc.identifier.source | Immunogenetics | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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