A mouse Y Chromosome pseudogene is related to human ubiquitin activating enzyme E1
dc.contributor.author | Tucker, Priscilla K. | en_US |
dc.contributor.author | Phillips, Kimberly S. | en_US |
dc.contributor.author | Lundrigan, Barbara L. | en_US |
dc.date.accessioned | 2006-09-11T18:27:52Z | |
dc.date.available | 2006-09-11T18:27:52Z | |
dc.date.issued | 1992-01 | en_US |
dc.identifier.citation | Tucker, Priscilla K.; Phillips, Kimberly S.; Lundrigan, Barbara; (1992). "A mouse Y Chromosome pseudogene is related to human ubiquitin activating enzyme E1 ." Mammalian Genome 3(1): 28-35. <http://hdl.handle.net/2027.42/46990> | en_US |
dc.identifier.issn | 0938-8990 | en_US |
dc.identifier.issn | 1432-1777 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/46990 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1581630&dopt=citation | en_US |
dc.description.abstract | A 2041 bp DNA fragment isolated from the Sxr (sex reversed) region of the mouse Y Chromosome (Chr) was sequenced and characterized. The sequence, pY8/b, contains four exons that are highly similar to 525 contiguous bases from the cDNA of human ubiquitin activating enzyme El . Two of the exons contain stop codons, indicating that pY8/b is not part of a functional gene. Sequences related to pY8/b were amplified from the Y Chr of the inbred mouse strain, C57BL/6J. These sequences may be portions of the recently discovered functional equivalent of pY8/b. Despite a high degree of similarity with the human El gene, the functional equivalent of pY8/b is not the mouse El gene, because unlike El , the functional equivalent of pY8/b is expressed in a tissue-specific manner. These data are discussed with respect to theory on the evolution of the mammalian Y Chr, and in particular, to the prediction that functional genes on the Y Chr have a male-specific function. | en_US |
dc.format.extent | 770533 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Cell Biology | en_US |
dc.subject.other | Life Sciences | en_US |
dc.subject.other | Anatomy | en_US |
dc.subject.other | Zoology | en_US |
dc.title | A mouse Y Chromosome pseudogene is related to human ubiquitin activating enzyme E1 | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Natural Resources and Environment | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbsecondlevel | Ecology and Evolutionary Biology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | The Museum of Zoology, University of Michigan, 48 109, Ann Arbor, Michigan, USA; Department of Biology, University of Michigan, 48 109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | The Museum of Zoology, University of Michigan, 48 109, Ann Arbor, Michigan, USA; Department of Biology, University of Michigan, 48 109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationum | The Museum of Zoology, University of Michigan, 48 109, Ann Arbor, Michigan, USA; Department of Biology, University of Michigan, 48 109, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1581630 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/46990/1/335_2004_Article_BF00355838.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00355838 | en_US |
dc.identifier.source | Mammalian Genome | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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