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Molecular map of Chromosome 19 including three genes affecting bleeding time: ep, ru , and bm

dc.contributor.authorNovak, E. K.en_US
dc.contributor.authorKeller, Scot A.en_US
dc.contributor.authorO'Brien, E. P.en_US
dc.contributor.authorGuénet, J. -L.en_US
dc.contributor.authorPoirier, C.en_US
dc.contributor.authorSwank, Richard T.en_US
dc.date.accessioned2006-09-11T18:29:19Z
dc.date.available2006-09-11T18:29:19Z
dc.date.issued1994-06en_US
dc.identifier.citationO'Brien, E. P.; Novak, E. K.; Keller, S. A.; Poirier, C.; Guénet, J.-L.; Swank, R. T.; (1994). "Molecular map of Chromosome 19 including three genes affecting bleeding time: ep, ru , and bm ." Mammalian Genome 5(6): 356-360. <http://hdl.handle.net/2027.42/47011>en_US
dc.identifier.issn0938-8990en_US
dc.identifier.issn1432-1777en_US
dc.identifier.urihttps://hdl.handle.net/2027.42/47011
dc.identifier.urihttp://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=8043950&dopt=citationen_US
dc.description.abstractThe mouse ruby eye ( ru ) and pale ear ( ep ) pigment dilution genes cause platelet storage pool deficiency (SPD) and prolonged bleeding times. The brachymorphic ( bm ) gene, in addition to causing skeletal abnormalities, is also associated with prolonged bleeding times. All three hemorrhagic genes are found within 10 cM on Chromosome (Chr) 19. In this study, 15 microsatellite markers and five cDNAs, spanning 21 cM of Chr 19, were mapped in relation to the bm, ep , and ru genes in 457 progeny of an interspecific backcross utilizing the highly inbred strain PWK derived from the Mus musculus musculus species. Several markers were found to be closely linked to the three genes and should be useful as entry points in their eventual molecular identification.en_US
dc.format.extent597655 bytes
dc.format.extent3115 bytes
dc.format.mimetypeapplication/pdf
dc.format.mimetypetext/plain
dc.language.isoen_US
dc.publisherSpringer-Verlagen_US
dc.subject.otherCell Biologyen_US
dc.subject.otherLife Sciencesen_US
dc.subject.otherAnatomyen_US
dc.subject.otherZoologyen_US
dc.titleMolecular map of Chromosome 19 including three genes affecting bleeding time: ep, ru , and bmen_US
dc.typeArticleen_US
dc.subject.hlbsecondlevelNatural Resources and Environmenten_US
dc.subject.hlbsecondlevelMolecular, Cellular and Developmental Biologyen_US
dc.subject.hlbsecondlevelEcology and Evolutionary Biologyen_US
dc.subject.hlbtoplevelHealth Sciencesen_US
dc.subject.hlbtoplevelScienceen_US
dc.description.peerreviewedPeer Revieweden_US
dc.contributor.affiliationumDepartment of Human Genetics, University of Michigan, 48109, Ann Arbor, Michigan, USAen_US
dc.contributor.affiliationotherUnité de Génétique des Mammiféres, Institut Pasteur de Paris, 75724, Paris Cedex 15, Franceen_US
dc.contributor.affiliationotherMolecular and Cellular Biology Department, Roswell Park Cancer Institute, Carlton and Elm Streets, 14263, Buffalo, New York, USAen_US
dc.contributor.affiliationotherUnité de Génétique des Mammiféres, Institut Pasteur de Paris, 75724, Paris Cedex 15, Franceen_US
dc.contributor.affiliationotherMolecular and Cellular Biology Department, Roswell Park Cancer Institute, Carlton and Elm Streets, 14263, Buffalo, New York, USAen_US
dc.contributor.affiliationotherMolecular and Cellular Biology Department, Roswell Park Cancer Institute, Carlton and Elm Streets, 14263, Buffalo, New York, USAen_US
dc.contributor.affiliationumcampusAnn Arboren_US
dc.identifier.pmid8043950en_US
dc.description.bitstreamurlhttp://deepblue.lib.umich.edu/bitstream/2027.42/47011/1/335_2004_Article_BF00356554.pdfen_US
dc.identifier.doihttp://dx.doi.org/10.1007/BF00356554en_US
dc.identifier.sourceMammalian Genomeen_US
dc.owningcollnameInterdisciplinary and Peer-Reviewed


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