Idiopathic prolactin cell hyperplasia of the pituitary mimicking prolactin cell adenoma: a morphological study including immunocytochemistry, electron microscopy, and in situ hybridization
dc.contributor.author | Kovacs, Kalman | en_US |
dc.contributor.author | Horvath, Eva | en_US |
dc.contributor.author | Smyth, H. S. | en_US |
dc.contributor.author | Lloyd, Ricardo V. | en_US |
dc.contributor.author | Jay, V. | en_US |
dc.date.accessioned | 2006-09-11T18:44:23Z | |
dc.date.available | 2006-09-11T18:44:23Z | |
dc.date.issued | 1991-07 | en_US |
dc.identifier.citation | Jay, V.; Kovacs, K.; Horvath, E.; Lloyd, R. V.; Smyth, H. S.; (1991). "Idiopathic prolactin cell hyperplasia of the pituitary mimicking prolactin cell adenoma: a morphological study including immunocytochemistry, electron microscopy, and in situ hybridization." Acta Neuropathologica 82(2): 147-151. <http://hdl.handle.net/2027.42/47231> | en_US |
dc.identifier.issn | 1432-0533 | en_US |
dc.identifier.issn | 0001-6322 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47231 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1927271&dopt=citation | en_US |
dc.description.abstract | Prolactin cell adenoma is the most frequently found lesion in surgically removed pituitaries of patients with hyperprolactinemia. However, in several instances, instead of prolactin cell adenoma, other lesions are encountered by morphological investigation. We report here the morphological findings in a patient with hyperprolactinemia who underwent transsphenoidal pituitary surgery for suspected prolactin cell adenoma. A morphological diagnosis of tumor could not be confirmed and massive diffuse prolactin cell hyperplasia was identified. The aim of this publication is to describe the lesion by histology, immunocytochemistry, electron microscopy, and in situ hybridization and to call attention to primary prolactin cell hyperplasia which can mimic prolactin cell adenoma. | en_US |
dc.format.extent | 1638353 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Ultrastructure | en_US |
dc.subject.other | Pathology | en_US |
dc.subject.other | Pathology | en_US |
dc.subject.other | Prolactin | en_US |
dc.subject.other | Hyperplasia | en_US |
dc.subject.other | Pituitary | en_US |
dc.subject.other | Medicine & Public Health | en_US |
dc.title | Idiopathic prolactin cell hyperplasia of the pituitary mimicking prolactin cell adenoma: a morphological study including immunocytochemistry, electron microscopy, and in situ hybridization | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Pathology | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA | en_US |
dc.contributor.affiliationother | Department of Pathology, St. Michael's Hospital, Toronto, Canada | en_US |
dc.contributor.affiliationother | Department of Pathology, The Princess Margaret Hospital, 555 University Avenue, M5G 1X8, Toronto, Ontario, Canada; The Hospital for Sick Children-University of Toronto, 555 University Avenue, M5G 1X8, Toronto, Ontario, Canada | en_US |
dc.contributor.affiliationother | Department of Pathology, St. Michael's Hospital, Toronto, Canada | en_US |
dc.contributor.affiliationother | Department of Neurosurgery, Wellesley Hospital, Toronto, Canada | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1927271 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47231/1/401_2004_Article_BF00293958.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00293958 | en_US |
dc.identifier.source | Acta Neuropathologica | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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