Regeneration in grafts of normal and denervated rat muscles
dc.contributor.author | Gutmann, Ernest | en_US |
dc.contributor.author | Carlson, Bruce M. | en_US |
dc.date.accessioned | 2006-09-11T18:59:05Z | |
dc.date.available | 2006-09-11T18:59:05Z | |
dc.date.issued | 1975-09 | en_US |
dc.identifier.citation | Carlson, Bruce M.; Gutmann, Ernest; (1975). "Regeneration in grafts of normal and denervated rat muscles." Pflügers Archiv European Journal of Physiology 353(3): 215-225. <http://hdl.handle.net/2027.42/47443> | en_US |
dc.identifier.issn | 1432-2013 | en_US |
dc.identifier.issn | 0031-6768 | en_US |
dc.identifier.uri | https://hdl.handle.net/2027.42/47443 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=retrieve&db=pubmed&list_uids=1168337&dopt=citation | en_US |
dc.description.abstract | The soleus or extensor digitorum longus muscles of young rats were freely grafted into the bed of the corresponding contralateral muscle. The grafts were of normal muscle or muscles which had been denervated for 14 days. Grafts of normal muscle were characterized by little or no contractile activity for the first 2–4 days after transplantation. In contrast, denervated grafts contracted weakly, but consistently, throughout this early period. The patterns of contraction were complex. In early transplants, the contractions were due entirely to surviving muscle fibers in the graft, and the contractile characteristics were those of denervated muscle fibers. After the first week, contractions of newly regenerating muscle fibers within the grafts were superimposed upon and later took over those from the fibers that survived the original transplantation. The contraction time approached those of the normal soleus or extensor muscles during the second month after grafting, and the grafts contracted like fast or slow muscles. | en_US |
dc.format.extent | 529860 bytes | |
dc.format.extent | 3115 bytes | |
dc.format.mimetype | application/pdf | |
dc.format.mimetype | text/plain | |
dc.language.iso | en_US | |
dc.publisher | Springer-Verlag | en_US |
dc.subject.other | Biomedicine | en_US |
dc.subject.other | Muscle Regeneration | en_US |
dc.subject.other | Muscle Transplantation | en_US |
dc.subject.other | Human Physiology | en_US |
dc.subject.other | Denervation of Muscle | en_US |
dc.subject.other | Contractile Properties of Muscle Transplants | en_US |
dc.subject.other | Rat | en_US |
dc.title | Regeneration in grafts of normal and denervated rat muscles | en_US |
dc.type | Article | en_US |
dc.subject.hlbsecondlevel | Kinesiology and Sports | en_US |
dc.subject.hlbsecondlevel | Molecular, Cellular and Developmental Biology | en_US |
dc.subject.hlbtoplevel | Science | en_US |
dc.subject.hlbtoplevel | Health Sciences | en_US |
dc.description.peerreviewed | Peer Reviewed | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Michigan, Ann Arbor, Michigan, USA; Institute of Physiology, Czechoslovak Academy of Sciences, Prague, Czechoslovakia | en_US |
dc.contributor.affiliationum | Department of Anatomy, University of Michigan, Ann Arbor, Michigan, USA; Institute of Physiology, Czechoslovak Academy of Sciences, Prague, Czechoslovakia | en_US |
dc.contributor.affiliationumcampus | Ann Arbor | en_US |
dc.identifier.pmid | 1168337 | en_US |
dc.description.bitstreamurl | http://deepblue.lib.umich.edu/bitstream/2027.42/47443/1/424_2004_Article_BF00584285.pdf | en_US |
dc.identifier.doi | http://dx.doi.org/10.1007/BF00584285 | en_US |
dc.identifier.source | Pflügers Archiv European Journal of Physiology | en_US |
dc.owningcollname | Interdisciplinary and Peer-Reviewed |
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